No. J0640 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What is one billing unit of J0640?

One unit of J0640 is 50 mg, as stated in the code's descriptor. Units to report = dose given ÷ 50 mg.

J0640 (Retired 2026) — Leucovorin calcium injection

J0640 was retired on Sep 30, 2026

CMS ended J0640 after Sep 30, 2026. Don’t report it for later dates of service. Current codes for the same drug:

Code

CMS HCPCS file

HCPCS codeJ0640

Billing unit50 mg

Descriptor: Injection, leucovorin calcium, per 50 mg
Short descriptor: Leucovorin calcium injection
Code set: HCPCS Level II, maintained by CMS
Effective: Oct 1, 2026

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Find the NDC

Med-Code hasn’t mapped J0640 to specific products yet. Search the FDA NDC Directory for the drug named in the descriptor, and check the route and strength match the code.

Search NDCs for leucovorin calcium

J0640: common questions

Is J0640 a CPT code?: No. J0640 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What is one billing unit of J0640?: One unit of J0640 is 50 mg, as stated in the code's descriptor. Units to report = dose given ÷ 50 mg. J-code billing units.

J0640 — Injection, leucovorin calcium, per 50 mg

Code

Find the NDC

J0640: common questions

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