HCPCS Level II drug code
J0640 — Injection, leucovorin calcium, per 50 mg
In short
J0640 is the HCPCS Level II code for injection, leucovorin calcium, per 50 mg. One billing unit is 50 mg.
J0640 ends on Sep 30, 2026
CMS is discontinuing J0640; it can’t be reported for dates of service after Sep 30, 2026.
Code
CMS HCPCS fileHCPCS codeJ0640
Billing unit50 mg
- Descriptor
- Injection, leucovorin calcium, per 50 mg
- Short descriptor
- Leucovorin calcium injection
- Code set
- HCPCS Level II, maintained by CMS
- Effective
- Oct 1, 2026
The billing unit is read from the descriptor. Confirm it against the CMS file before billing.
Units and claim line
Units = dose given ÷ 50 mg. For example, 5000 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Find the NDC
Med-Code hasn’t mapped J0640 to specific products yet. Search the FDA NDC Directory for the drug named in the descriptor, and check the route and strength match the code.
J0640: common questions
- Is J0640 a CPT code?
- No. J0640 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
- What is one billing unit of J0640?
- One unit of J0640 is 50 mg, as stated in the code's descriptor. Units to report = dose given ÷ 50 mg. J-code billing units.