In short

J0780 is the HCPCS Level II code for injection, prochlorperazine, up to 10 mg. CMS assigns NDCs for Prochlorperazine Edisylate to it. The Medicare Part B payment limit is $2.475 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ0780
Billing unitSee descriptor
Descriptor
Injection, prochlorperazine, up to 10 mg
Short descriptor
Prochlorperazine injection
Code set
HCPCS Level II, maintained by CMS
Effective
Jan 1, 1997

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$2.475
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

NDCs billed under J0780

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 18 NDCs to J0780 for Prochlorperazine Edisylate. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J0780 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Prochlorperazine Edisylate00641-6135-25Hikma Pharmaceuticals USA Inc.25 × 225
Prochlorperazine Edisylate14789-0700-02Nexus Pharmaceuticals, LLC10 × 210
Prochlorperazine Edisylate23155-0294-41Heritage Pharmaceuticals Inc.25 × 225
Prochlorperazine Edisylate23155-0294-42Heritage Pharmaceuticals Inc.10 × 210
Prochlorperazine Edisylate23155-0497-42Heritage Pharmaceuticals Inc.10 × 210
Prochlorperazine Edisylate23155-0523-41Heritage Pharmaceuticals Inc.10 × 210
Prochlorperazine Edisylate25021-0790-02Sagent Pharmaceuticals10 × 210
Prochlorperazine Edisylate25021-0790-03Sagent Pharmaceuticals25 × 225
Prochlorperazine Edisylate43066-0090-25Baxter Healthcare Corporation25 × 225
Prochlorperazine Edisylate51662-1558-03HF Acquisition Co. LLC, DBA HealthFirst25 × 225
Prochlorperazine Edisylate65145-0119-10Caplin Steriles USA Inc.10 × 210
Prochlorperazine Edisylate67457-0640-02Mylan Institutional LLC25 × 225
Prochlorperazine Edisylate67457-0640-99Mylan Institutional LLC10 × 210
Prochlorperazine Edisylate70069-0371-25Somerset Pharma, LLC25 × 225
Prochlorperazine Edisylate70860-0778-02Athenex Pharmaceutical Division, LLC10 × 210
Prochlorperazine Edisylate72266-0204-10Fosun Pharma USA Inc.10 × 210
Prochlorperazine Edisylate72572-0580-25Civica, Inc.25 × 225
Prochlorperazine Edisylate83634-0778-02Avenacy Inc.10 × 210

J0780: common questions

Is J0780 a CPT code?
No. J0780 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J0780?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 18 NDCs under J0780, for Prochlorperazine Edisylate. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J0780?
$2.475 per 10 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

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