No. J1448 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDCs are billed under J1448?

CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 2 NDCs under J1448, for Cosela. The table on this page shows each one with its billing units per package.

What is the Medicare payment limit for J1448?

$6.001 per 1 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

What is one billing unit of J1448?

One unit of J1448 is 1mg, as stated in the code's descriptor. Units to report = dose given ÷ 1mg.

J1448 J-Code: Cosela (trilaciclib) — Billing Units & NDCs

In short

J1448 is the HCPCS Level II code for injection, trilaciclib, 1mg. CMS assigns NDCs for Cosela to it. One billing unit is 1mg. The Medicare Part B payment limit is $6.001 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file

HCPCS codeJ1448

Billing unit1mg

Descriptor: Injection, trilaciclib, 1mg
Short descriptor: Injection, trilaciclib, 1mg
Code set: HCPCS Level II, maintained by CMS
Effective: Oct 1, 2021

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$6.001

Per1 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 1mg. For example, 100 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 1 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

NDCs billed under J1448

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 2 NDCs to J1448 for Cosela. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J1448 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Cosela	73462-0101-01	G1 Therapeutics, Inc.	1	300
Cosela	73594-0101-01	Pharmacosmos Therapeutics Inc.	1	300

J1448: common questions

Is J1448 a CPT code?: No. J1448 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J1448?: CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 2 NDCs under J1448, for Cosela. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J1448?: $6.001 per 1 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J1448?: One unit of J1448 is 1mg, as stated in the code's descriptor. Units to report = dose given ÷ 1mg. J-code billing units.

J1448 — Injection, trilaciclib, 1mg