In short

J1957 is the HCPCS Level II code for injection, levetiracetam, 5 mg. CMS assigns NDCs for Keppra and Levetiracetam to it. One billing unit is 5 mg. The Medicare Part B payment limit is $0.013 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ1957
Billing unit5 mg
Descriptor
Injection, levetiracetam, 5 mg
Short descriptor
Injection levetiracetam 5 mg
Code set
HCPCS Level II, maintained by CMS
Effective
Oct 1, 2026

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.013
Per5 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Added October 2026. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 5 mg. For example, 500 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

NDCs billed under J1957

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 15 NDCs to J1957 for Keppra and Levetiracetam. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J1957 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Keppra50474-0002-63UCB, Inc.10 × 51,000
Levetiracetam00143-9574-25Hikma Pharmaceuticals USA Inc.25 × 52,500
Levetiracetam00143-9673-25Hikma Pharmaceuticals USA Inc.25 × 52,500
Levetiracetam00409-1886-02Pfizer Inc25 × 52,500
Levetiracetam00409-2011-25Pfizer Inc25 × 52,500
Levetiracetam25021-0780-05Sagent Pharmaceuticals10 × 51,000
Levetiracetam55150-0177-05Eugia US LLC10 × 51,000
Levetiracetam63323-0400-05FreseniUS Kabi USA, LLC10 × 51,000
Levetiracetam63323-0400-44FreseniUS Kabi USA, LLC10 × 51,000
Levetiracetam67457-0790-05Mylan Institutional LLC10 × 51,000
Levetiracetam72205-0120-07Novadoz Pharmaceuticals LLC10 × 51,000
Levetiracetam72205-0120-25Novadoz Pharmaceuticals LLC25 × 52,500
Levetiracetam72485-0106-10Armas Pharmaceuticals Inc.10 × 51,000
Levetiracetam72485-0106-25Armas Pharmaceuticals Inc.25 × 52,500
Levetiracetam72572-0360-25Civica, Inc.25 × 52,500

J1957: common questions

Is J1957 a CPT code?
No. J1957 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J1957?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 15 NDCs under J1957, for Keppra and Levetiracetam. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J1957?
$0.013 per 5 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J1957?
One unit of J1957 is 5 mg, as stated in the code's descriptor. Units to report = dose given ÷ 5 mg. J-code billing units.

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