In short

J2359 is the HCPCS Level II code for injection, olanzapine, 0.5 mg. CMS assigns NDCs for Olanzapine to it. One billing unit is 0.5 mg. The Medicare Part B payment limit is $0.615 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ2359
Billing unit0.5 mg
Descriptor
Injection, olanzapine, 0.5 mg
Short descriptor
Inj. olanzapine, 0.5mg
Code set
HCPCS Level II, maintained by CMS
Effective
Jan 1, 2024

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.615
Per0.5 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 0.5 mg. For example, 50 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

NDCs billed under J2359

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 9 NDCs to J2359 for Olanzapine. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J2359 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Olanzapine00121-1072-55PAI Holdings, LLC120
Olanzapine00143-9199-01Hikma Pharmaceuticals USA Inc.120
Olanzapine00517-0955-01American Regent, Inc.120
Olanzapine00781-3159-72Sandoz Inc.120
Olanzapine00781-9105-72Sandoz Inc.120
Olanzapine39822-1800-01XGen Pharmaceuticals DJB, Inc.120
Olanzapine55150-0308-01Eugia US LLC120
Olanzapine68462-0952-10Glenmark Pharmaceuticals Inc., USA120
Olanzapine72603-0181-01Northstar RxLLC120

J2359: common questions

Is J2359 a CPT code?
No. J2359 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J2359?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 9 NDCs under J2359, for Olanzapine. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J2359?
$0.615 per 0.5 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J2359?
One unit of J2359 is 0.5 mg, as stated in the code's descriptor. Units to report = dose given ÷ 0.5 mg. J-code billing units.

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