No. J2597 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDCs are billed under J2597?

CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 21 NDCs under J2597, for Ddavp and Desmopressin Acetate. The table on this page shows each one with its billing units per package.

What is the Medicare payment limit for J2597?

$3.475 per 1 mcg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

What is one billing unit of J2597?

One unit of J2597 is 1 mcg, as stated in the code's descriptor. Units to report = dose given ÷ 1 mcg.

J2597 J-Code: Ddavp (desmopressin acetate) — Billing Units

In short

J2597 is the HCPCS Level II code for injection, desmopressin acetate, per 1 mcg. CMS assigns NDCs for Ddavp and Desmopressin Acetate to it. One billing unit is 1 mcg. The Medicare Part B payment limit is $3.475 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file

HCPCS codeJ2597

Billing unit1 mcg

Descriptor: Injection, desmopressin acetate, per 1 mcg
Short descriptor: Inj desmopressin acetate
Code set: HCPCS Level II, maintained by CMS
Effective: Jan 1, 1997

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$3.475

Per1 mcg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 1 mcg. For example, 100 mcg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Dose given (mcg)

HCPCS units (1 unit = 1 mcg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

NDCs billed under J2597

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 21 NDCs to J2597 for Ddavp and Desmopressin Acetate. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J2597 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Ddavp	55566-2200-00	Ferring Pharmaceuticals Inc.	10 × 1	40
Ddavp	55566-2300-00	Ferring Pharmaceuticals Inc.	10	40
Desmopressin Acetate	25021-0460-01	Sagent Pharmaceuticals	10 × 1	40
Desmopressin Acetate	25021-0461-10	Sagent Pharmaceuticals	10	40
Desmopressin Acetate	39822-6200-02	XGen Pharmaceuticals DJB, Inc.	10 × 1	40
Desmopressin Acetate	39822-6250-01	XGen Pharmaceuticals DJB, Inc.	10	40
Desmopressin Acetate	43598-0053-11	Dr. Reddy's Laboratories Inc.	10	40
Desmopressin Acetate	43598-0931-09	Dr. Reddy's Laboratories Inc.	10 × 1	40
Desmopressin Acetate	65219-0293-01	FreseniUS Kabi USA, LLC	10 × 1	40
Desmopressin Acetate	65219-0295-10	FreseniUS Kabi USA, LLC	10	40
Desmopressin Acetate	69918-0899-10	Nordic Pharma, Inc	10 × 1	40
Desmopressin Acetate	69918-0899-11	Nordic Pharma, Inc	10 × 1	40
Desmopressin Acetate	69918-0901-10	Nordic Pharma, Inc	10	40
Desmopressin Acetate	69918-0901-11	Nordic Pharma, Inc	10	40
Desmopressin Acetate	69918-0901-12	Nordic Pharma, Inc	10	40
Desmopressin Acetate	70095-0026-02	Sun Pharmaceutical Industries, Inc.	10 × 1	40
Desmopressin Acetate	70095-0031-01	Sun Pharmaceutical Industries, Inc.	10	40
Desmopressin Acetate	70860-0454-01	Athenex Pharmaceutical Division, LLC	10 × 1	40
Desmopressin Acetate	70860-0454-10	Athenex Pharmaceutical Division, LLC	10	40
Desmopressin Acetate	83634-0451-01	Avenacy Inc.	10 × 1	40
Desmopressin Acetate	83634-0451-10	Avenacy Inc.	10	40

J2597: common questions

Is J2597 a CPT code?: No. J2597 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J2597?: CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 21 NDCs under J2597, for Ddavp and Desmopressin Acetate. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J2597?: $3.475 per 1 mcg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J2597?: One unit of J2597 is 1 mcg, as stated in the code's descriptor. Units to report = dose given ÷ 1 mcg. J-code billing units.

J2597 — Injection, desmopressin acetate, per 1 mcg