No. J2778 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDCs are billed under J2778?

CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 2 NDCs under J2778, for Lucentis and Lucentis PFS. The table on this page shows each one with its billing units per package.

What is the Medicare payment limit for J2778?

$26.384 per 0.1 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

What is one billing unit of J2778?

One unit of J2778 is 0.1 mg, as stated in the code's descriptor. Units to report = dose given ÷ 0.1 mg.

J2778 J-Code: Lucentis, Lucentis PFS (ranibizumab)

In short

J2778 is the HCPCS Level II code for injection, ranibizumab, 0.1 mg. CMS assigns NDCs for Lucentis and Lucentis PFS to it. One billing unit is 0.1 mg. The Medicare Part B payment limit is $26.384 per unit (October 1, 2026 through December 31, 2026).

Code

Med-Code curated

HCPCS codeJ2778

Billing unit0.1 mg

Descriptor: Injection, ranibizumab, 0.1 mg
Code set: HCPCS Level II, maintained by CMS
Category: Ophthalmic / Anti-VEGF

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$26.384

Per0.1 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 0.1 mg. For example, 10 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 0.1 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

Drugs mapped to J2778

FDA-listed products billed under J2778

Finished products in the FDA NDC Directory whose brand or single active ingredient, and route, match this code’s entry.

NDC products matching J2778
Product	Strength	Form · route	Labeler	Product NDC
Byoovizranibizumab-nuna	Ranibizumab 10 mg/mL	Injection, SolutionIntravitreal	BIOGEN INC.	64406-019
Byoovizranibizumab-nuna	Ranibizumab 10 mg/mL	Injection, SolutionIntravitreal	Harrow Eye, LLC	82667-018
Cimerliranibizumab-eqrn	Ranibizumab .3 mg/.05mL	Injection, SolutionIntravitreal	Sandoz Inc	61314-624
Cimerliranibizumab-eqrn	Ranibizumab .5 mg/.05mL	Injection, SolutionIntravitreal	Sandoz Inc	61314-625
Cimerliranibizumab-eqrn	Ranibizumab .3 mg/.05mL	Injection, SolutionIntravitreal	Coherus BioSciences Inc	70114-440
Cimerliranibizumab-eqrn	Ranibizumab .5 mg/.05mL	Injection, SolutionIntravitreal	Coherus BioSciences Inc	70114-441
Lucentisranibizumab	Ranibizumab 10 mg/mL	Injection, SolutionIntravitreal	Genentech, Inc.	50242-080
Lucentisranibizumab	Ranibizumab 6 mg/mL	Injection, SolutionIntravitreal	Genentech, Inc.	50242-082
Nufymcoranibizumab-leyk	Ranibizumab .3 mg/.05mL	Injection, SolutionIntravitreal	Zydus Pharmaceuticals USA Inc.	70710-2172
Nufymcoranibizumab-leyk	Ranibizumab .5 mg/.05mL	Injection, SolutionIntravitreal	Zydus Pharmaceuticals USA Inc.	70710-2173
Susvimoranibizumab	Ranibizumab 100 mg/mL	Injection, SolutionIntravitreal	Genentech, Inc.	50242-078

All NDCs for these drugs

NDCs billed under J2778

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 2 NDCs to J2778 for Lucentis and Lucentis PFS. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J2778 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Lucentis	50242-0080-03	Genentech, Inc.	0.05	5
Lucentis PFS	50242-0082-03	Genentech, Inc.	0.05	3

J2778: common questions

Is J2778 a CPT code?: No. J2778 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J2778?: CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 2 NDCs under J2778, for Lucentis and Lucentis PFS. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J2778?: $26.384 per 0.1 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J2778?: One unit of J2778 is 0.1 mg, as stated in the code's descriptor. Units to report = dose given ÷ 0.1 mg. J-code billing units.

J2778 — Injection, ranibizumab, 0.1 mg