In short

J3246 is the HCPCS Level II code for injection, tirofiban hcl, 0.25 mg. CMS assigns NDCs for Tirofiban to it. One billing unit is 0.25 mg. The Medicare Part B payment limit is $2.615 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ3246
Billing unit0.25 mg
Descriptor
Injection, tirofiban hcl, 0.25 mg
Short descriptor
Tirofiban hcl
Code set
HCPCS Level II, maintained by CMS
Effective
Jan 1, 2024

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$2.615
Per0.25 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Please see the NDC-HCPCS crosswalk for payable NDCs associated with this code. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 0.25 mg. For example, 25 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

NDCs billed under J3246

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 5 NDCs to J3246 for Tirofiban. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J3246 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Tirofiban14789-0102-05Nexus Pharmaceuticals, LLC25050
Tirofiban14789-0102-10Nexus Pharmaceuticals, LLC2 × 250100
Tirofiban25021-0417-84Sagent Pharmaceuticals25050
Tirofiban55150-0429-01Eugia US LLC10020
Tirofiban55150-0430-01Eugia US LLC25050

J3246: common questions

Is J3246 a CPT code?
No. J3246 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J3246?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 5 NDCs under J3246, for Tirofiban. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J3246?
$2.615 per 0.25 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J3246?
One unit of J3246 is 0.25 mg, as stated in the code's descriptor. Units to report = dose given ÷ 0.25 mg. J-code billing units.

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