No. J7181 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDCs are billed under J7181?

CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 1 NDC under J7181, for Tretten. The table on this page shows each one with its billing units per package.

What is the Medicare payment limit for J7181?

$19.328 per 1 iu, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

J7181 J-Code: Tretten (factor xiii a-subunit)

In short

J7181 is the HCPCS Level II code for injection, factor xiii a-subunit, (recombinant), per iu. CMS assigns NDCs for Tretten to it. The Medicare Part B payment limit is $19.328 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file

HCPCS codeJ7181

Billing unitSee descriptor

Descriptor: Injection, factor xiii a-subunit, (recombinant), per iu
Short descriptor: Factor xiii recomb a-subunit
Code set: HCPCS Level II, maintained by CMS
Effective: Jan 1, 2024

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$19.328

Per1 iu

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

HCPCS units

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the units to build the claim line.

NDCs billed under J7181

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 1 NDC to J7181 for Tretten. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J7181 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Tretten	00169-7013-01	Novo Nordisk, Inc	1	1

J7181: common questions

Is J7181 a CPT code?: No. J7181 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J7181?: CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 1 NDC under J7181, for Tretten. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J7181?: $19.328 per 1 iu, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

J7181 — Injection, factor xiii a-subunit, (recombinant), per iu