In short

J7354 is the HCPCS Level II code for cantharidin for topical administration, 0.7%, single unit dose applicator (3.2 mg). CMS assigns NDCs for Ycanth to it. The Medicare Part B payment limit is $683.472 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ7354
Billing unitSee descriptor
Descriptor
Cantharidin for topical administration, 0.7%, single unit dose applicator (3.2 mg)
Short descriptor
Cantharidin top, applicator
Code set
HCPCS Level II, maintained by CMS
Effective
Apr 1, 2024

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$683.472
Perper 3.2 mg single-use applicator
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

NDCs billed under J7354

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 2 NDCs to J7354 for Ycanth. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J7354 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Ycanth71349-0070-06Verrica Pharmaceuticals, Inc.6 × 0.456
Ycanth71349-0070-11Verrica Pharmaceuticals, Inc.0.451

J7354: common questions

Is J7354 a CPT code?
No. J7354 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J7354?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 2 NDCs under J7354, for Ycanth. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J7354?
$683.472 per per 3.2 mg single-use applicator, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

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