No. J9289 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDCs are billed under J9289?

CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 2 NDCs under J9289, for Opdivo Qvantig. The table on this page shows each one with its billing units per package.

What is the Medicare payment limit for J9289?

$27.989 per 2 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

What is one billing unit of J9289?

One unit of J9289 is 2 mg and hyaluronidase-nvhy, as stated in the code's descriptor. Units to report = dose given ÷ 2 mg and hyaluronidase-nvhy.

J9289 J-Code: Opdivo Qvantig (nivolumab) — Billing Units

In short

J9289 is the HCPCS Level II code for injection, nivolumab, 2 mg and hyaluronidase-nvhy. CMS assigns NDCs for Opdivo Qvantig to it. One billing unit is 2 mg and hyaluronidase-nvhy. The Medicare Part B payment limit is $27.989 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file

HCPCS codeJ9289

Billing unit2 mg and hyaluronidase-nvhy

Descriptor: Injection, nivolumab, 2 mg and hyaluronidase-nvhy
Short descriptor: Inj nivolumab 2 mg hyaluron
Code set: HCPCS Level II, maintained by CMS
Effective: Jul 1, 2025

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$27.989

Per2 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 2 mg and hyaluronidase-nvhy. For example, 200 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 2 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

NDCs billed under J9289

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 2 NDCs to J9289 for Opdivo Qvantig. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J9289 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Opdivo Qvantig	00003-3120-01	E.R. Squibb & Sons, L.L.C.	2.5	150
Opdivo Qvantig	00003-6120-01	E.R. Squibb & Sons, L.L.C.	5	300

J9289: common questions

Is J9289 a CPT code?: No. J9289 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J9289?: CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 2 NDCs under J9289, for Opdivo Qvantig. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J9289?: $27.989 per 2 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J9289?: One unit of J9289 is 2 mg and hyaluronidase-nvhy, as stated in the code's descriptor. Units to report = dose given ÷ 2 mg and hyaluronidase-nvhy. J-code billing units.

J9289 — Injection, nivolumab, 2 mg and hyaluronidase-nvhy