No. Q0221 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What is one billing unit of Q0221?

One unit of Q0221 is 600 mg, as stated in the code's descriptor. Units to report = dose given ÷ 600 mg.

HCPCS Level II · retired code

Q0221 — Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), 600 mg

Q0221 was retired on Dec 12, 2024

CMS ended Q0221 after Dec 12, 2024. Don’t report it for later dates of service. Look up the drug for its current code.

Look up tixagevimab and cilgavimab

Code

CMS HCPCS file

HCPCS codeQ0221

Billing unit600 mg

Descriptor: Injection, tixagevimab and cilgavimab, for the pre-exposure prophylaxis only, for certain adults and pediatric individuals (12 years of age and older weighing at least 40kg) with no known sars-cov-2 exposure, who either have moderate to severely compromised immune systems or for whom vaccination with any available covid-19 vaccine is not recommended due to a history of severe adverse reaction to a covid-19 vaccine(s) and/or covid-19 vaccine component(s), 600 mg
Short descriptor: Tixagev and cilgav, 600mg
Code set: HCPCS Level II, maintained by CMS
Effective: Dec 13, 2024

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Find the NDC

Med-Code hasn’t mapped Q0221 to specific products yet. Search the FDA NDC Directory for the drug named in the descriptor, and check the route and strength match the code.

Search NDCs for tixagevimab and cilgavimab

Q0221: common questions

Is Q0221 a CPT code?: No. Q0221 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What is one billing unit of Q0221?: One unit of Q0221 is 600 mg, as stated in the code's descriptor. Units to report = dose given ÷ 600 mg. J-code billing units.