In short

Q5106 is the HCPCS Level II code for injection, epoetin alfa-epbx, biosimilar, (retacrit) (for non-esrd use), 1000 units. CMS assigns NDCs for Retacrit to it. One billing unit is 1000 units. The Medicare Part B payment limit is $8.171 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeQ5106
Billing unit1000 units
Descriptor
Injection, epoetin alfa-epbx, biosimilar, (retacrit) (for non-esrd use), 1000 units
Short descriptor
Inj retacrit non-esrd use
Code set
HCPCS Level II, maintained by CMS
Effective
Jan 1, 2020

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$8.171
Per1000 units
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 1000 units. For example, 100000 units is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

NDCs billed under Q5106

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 12 NDCs to Q5106 for Retacrit. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to Q5106 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Retacrit00069-1305-10Pfizer Inc10 × 120
Retacrit00069-1306-10Pfizer Inc10 × 130
Retacrit00069-1307-10Pfizer Inc10 × 140
Retacrit00069-1308-10Pfizer Inc10 × 1100
Retacrit00069-1309-04Pfizer Inc4 × 1160
Retacrit00069-1311-10Pfizer Inc10 × 1200
Retacrit00069-1318-10Pfizer Inc10 × 2100
Retacrit59353-0002-10Vifor (International) Inc.10 × 120
Retacrit59353-0003-10Vifor (International) Inc.10 × 130
Retacrit59353-0004-10Vifor (International) Inc.10 × 140
Retacrit59353-0120-10Vifor (International) Inc.10 × 1200
Retacrit59353-0220-10Vifor (International) Inc.10 × 2100

Q5106: common questions

Is Q5106 a CPT code?
No. Q5106 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under Q5106?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 12 NDCs under Q5106, for Retacrit. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for Q5106?
$8.171 per 1000 units, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of Q5106?
One unit of Q5106 is 1000 units, as stated in the code's descriptor. Units to report = dose given ÷ 1000 units. J-code billing units.

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