HCPCS Level II drug code
Q5159 — Injection, denosumab-dssb (ospomyv/xbryk), biosimilar, 1 mg
In short
Q5159 is the HCPCS Level II code for injection, denosumab-dssb (ospomyv/xbryk), biosimilar, 1 mg. One billing unit is 1 mg.
Code
CMS HCPCS fileHCPCS codeQ5159
Billing unit1 mg
- Descriptor
- Injection, denosumab-dssb (ospomyv/xbryk), biosimilar, 1 mg
- Short descriptor
- Inj, denosumab-dssb, 1 mg
- Code set
- HCPCS Level II, maintained by CMS
- Effective
- Oct 1, 2025
The billing unit is read from the descriptor. Confirm it against the CMS file before billing.
Units and claim line
Units = dose given ÷ 1 mg. For example, 100 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Find the NDC
Med-Code hasn’t mapped Q5159 to specific products yet. Search the FDA NDC Directory for the drug named in the descriptor, and check the route and strength match the code.
Q5159: common questions
- Is Q5159 a CPT code?
- No. Q5159 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
- What is one billing unit of Q5159?
- One unit of Q5159 is 1 mg, as stated in the code's descriptor. Units to report = dose given ÷ 1 mg. J-code billing units.