Aldactone (spironolactone) NDC 0025-1041

NDC codes

FDA NDC Directory

Product NDC (as listed)0025-1041Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00025-1041Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
0025-1041-31	00025104131	100 TABLET, FILM COATED in 1 BOTTLE (0025-1041-31)Marketed from Jan 21, 1960

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Aldactone
Generic name (nonproprietary): spironolactone
Active ingredients: Spironolactone — 50 mg/1
Dosage form: Tablet, Film coated
Route: Oral
Labeler: Pfizer Laboratories Div Pfizer Inc
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 012151
Marketing start: Jan 21, 1960
Listing expires: Dec 31, 2026
Other FDA classes: Aldosterone Antagonists (Mechanism)
Identifiers: Product ID 0025-1041_22946678-dcad-4518-9bc6-cbdf51a38c16SPL ID 22946678-dcad-4518-9bc6-cbdf51a38c16SPL set ID 0fed2822-3a03-4b64-9857-c682fcd462bcRxCUI 198222, 198223, 200817, 200820, 200825, 313096UNII 27O7W4T232UPC 0300251001314, 0300251031311, 0300251041310
Pharmacologic class: Aldosterone Antagonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400025104131 followed by a unit qualifier and the quantity

Package 00025-1041-31. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Nov 28, 2025.

Indications (excerpt from the label)

ALDACTONE is an aldosterone antagonist indicated for: • The treatment of NYHA Class III–IV heart failure and reduced ejection fraction to increase survival, manage edema, and to reduce the need for hospitalization for heart failure ( 1.1 ). • Use as an add-on therapy for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions ( 1.2 ). • The management of edema in adult patients who are cirrhotic when edema is not responsive to fluid and sodium restrictions and in the setting of nephrotic syndrome when treatment of the underlying disease, restriction of fluid and …

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 012151

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 012151
Product	Strength	Form · route	Labeler	Product NDC
Aldactonespironolactone	Spironolactone 100 mg/1	Tablet, Film coatedOral	Pfizer Laboratories Div Pfizer Inc	0025-1031
Aldactonespironolactone	Spironolactone 25 mg/1	Tablet, Film coatedOral	Pfizer Laboratories Div Pfizer Inc	0025-1001