NDC codes

FDA NDC Directory
Product NDC (as listed)0037-4401Labeler and product segments. Claims need a package NDC.
Product NDC at billing width00037-4401Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
0037-4401-0100037440101100 TABLET in 1 BOTTLE (0037-4401-01)Marketed from Nov 30, 1978

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Depen
Generic name (nonproprietary)
penicillamine
Active ingredients
Penicillamine — 250 mg/1
Dosage form
Tablet
Route
Oral
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 019854
Marketing start
Listing expires
Identifiers
Product ID 0037-4401_d5cb9986-f53c-4f8c-acb9-d5bdff6f07b2SPL ID d5cb9986-f53c-4f8c-acb9-d5bdff6f07b2SPL set ID 38f8ae60-b354-11de-8a39-0800200c9a66RxCUI 198071, 207370UNII GNN1DV99GXUPC 0300374401015
Pharmacologic class
Antirheumatic Agent

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400037440101 followed by a unit qualifier and the quantity

Package 00037-4401-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS DEPEN is indicated in the treatment of Wilson’s disease, cystinuria, and in patients with severe, active rheumatoid arthritis who have failed to respond to an adequate trial of conventional therapy. Available evidence suggests that DEPEN is not of value in ankylosing spondylitis. Wilson’s Disease - Wilson’s disease (hepatolenticular degeneration) results from the interaction of an inherited defect and an abnormality in copper metabolism. The metabolic defect, which is the consequence of the autosomal inheritance of one abnormal gene from each parent, manifests itself in a greater positive copper balance than normal. As a result, copper is deposited in several organs and appears e…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

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