NDC codes

FDA NDC Directory
Product NDC (as listed)0078-0674Labeler and product segments. Claims need a package NDC.
Product NDC at billing width00078-0674Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
0078-0674-61000780674611 VIAL, SINGLE-DOSE in 1 CARTON (0078-0674-61) / 4 mL in 1 VIAL, SINGLE-DOSEMarketed from Dec 21, 2016

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Hycamtin
Generic name (nonproprietary)
topotecan hydrochloride
Active ingredients
Topotecan hydrochloride — 4 mg/4mL
Dosage form
Injection, Powder, Lyophilized, For solution
Route
Intravenous
Labeler
Novartis Pharmaceuticals CorporationNDC labeler code 0078
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 020671
Marketing start
Listing expires
Other FDA classes
Topoisomerase Inhibitors (Mechanism)
Identifiers
Product ID 0078-0674_e6e4f66b-e398-44d3-a832-e5a809f3e861SPL ID e6e4f66b-e398-44d3-a832-e5a809f3e861SPL set ID eeee060c-a9ec-423e-a374-8484009f8524RxCUI 637550, 1799416UNII 956S425ZCY
Pharmacologic class
Topoisomerase Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N400078067461 followed by a unit qualifier and the quantity

Package 00078-0674-61. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

HYCAMTIN for injection is a topoisomerase inhibitor indicated for treatment of: Patients with metastatic ovarian cancer after disease progression on or after initial or subsequent chemotherapy, as a single agent ( 1.1 ) Patients with small cell lung cancer (SCLC) platinum-sensitive disease who progressed at least 60 days after initiation of first-line chemotherapy, as a single agent ( 1.2 ) Patients with Stage IV-B, recurrent, or persistent cervical cancer which is not amenable to curative treatment, in combination with cisplatin ( 1.3 ) 1.1 Ovarian Cancer HYCAMTIN ® for injection, as a single agent, is indicated for the treatment of patients with metastatic ovarian cancer after disease prog…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 0078-0674

What is NDC 0078-0674?
0078-0674 is the product NDC for Hycamtin (topotecan hydrochloride), Topotecan hydrochloride 4 mg/4mL injection, powder, lyophilized, for solution, listed with the FDA by Novartis Pharmaceuticals Corporation. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?
Hycamtin (Topotecan hydrochloride).
What is the active ingredient?
Topotecan hydrochloride.
Who is the labeler?
Novartis Pharmaceuticals Corporation, NDC labeler code 0078. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Hycamtin?
2 other product NDCs are listed under this name. See all Hycamtin NDCs.
Is there a related HCPCS / J-code?
Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Hycamtin NDCs
ProductStrengthForm · routeLabelerProduct NDCPackage NDCs (11-digit)
HycamtintopotecanTopotecan hydrochloride .25 mg/1CapsuleOralSandoz Inc66758-10166758-0101-11
HycamtintopotecanTopotecan hydrochloride 1 mg/1CapsuleOralSandoz Inc66758-10266758-0102-11

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