Estradiol Valerate NDC 0143-9290

NDC codes

FDA NDC Directory

Product NDC (as listed)0143-9290Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00143-9290Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
0143-9290-01	00143929001	1 VIAL in 1 CARTON (0143-9290-01) / 5 mL in 1 VIALMarketed from Apr 21, 2020

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Estradiol Valerate
Generic name (nonproprietary): estradiol valerate
Active ingredients: Estradiol valerate — 20 mg/mL
Dosage form: Injection
Route: Intramuscular
Labeler: Hikma Pharmaceuticals USA Inc.
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 203723
Marketing start: Apr 21, 2020
Listing expires: Dec 31, 2026
Other FDA classes: Estradiol Congeners (Chemical structure)Estrogen Receptor Agonists (Mechanism)
Identifiers: Product ID 0143-9290_5fa9d3b5-6bfd-40e9-900e-21427f6c4d21SPL ID 5fa9d3b5-6bfd-40e9-900e-21427f6c4d21SPL set ID 66f40ab0-4432-4e85-b709-a0bc076868c6RxCUI 310189, 310190, 310191UNII OKG364O896
Pharmacologic class: Estrogen

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N400143929001 followed by a unit qualifier and the quantity

Package 00143-9290-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Nov 10, 2025. This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS AND USAGE Estradiol Valerate Injection, USP is indicated in the: Treatment of moderate to severe vasomotor symptoms associated with the menopause. Treatment of moderate to severe symptoms of vulvar and vaginal atrophy associated with the menopause. When prescribing solely for the treatment of symptoms of vulvar and vaginal atrophy, topical vaginal products should be considered. Treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure. Treatment of advanced androgen-dependent carcinoma of the prostate (for palliation only).

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 203723

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 203723
Product	Strength	Form · route	Labeler	Product NDC
Estradiol Valerate	Estradiol valerate 10 mg/mL	InjectionIntramuscular	Hikma Pharmaceuticals USA Inc.	0143-9289
Estradiol Valerate	Estradiol valerate 40 mg/mL	InjectionIntramuscular	Hikma Pharmaceuticals USA Inc.	0143-9291