What is NDC 0143-9558?

0143-9558 is the product NDC for Levoleucovorin, Levoleucovorin calcium 50 mg/5mL injection, powder, lyophilized, for solution, listed with the FDA by Hikma Pharmaceuticals USA Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.

Hikma Pharmaceuticals USA Inc., NDC labeler code 0143. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Levoleucovorin?

6 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Levoleucovorin NDC 0143-9558 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)0143-9558Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00143-9558Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
0143-9558-01	0014395580100143955801	1 VIAL in 1 BOX (0143-9558-01) / 5 mL in 1 VIALMarketed from Jul 7, 2016

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Levoleucovorin
Generic name (nonproprietary): levoleucovorin
Active ingredients: Levoleucovorin calcium — 50 mg/5mL
Dosage form: Injection, Powder, Lyophilized, For solution
Route: Intravenous
Labeler: Hikma Pharmaceuticals USA Inc.NDC labeler code 0143
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 206263
Marketing start: Jul 7, 2016
Listing expires: Dec 31, 2026
Other FDA classes: Folic Acid (Chemical structure)
Identifiers: Product ID 0143-9558_d5427bbc-8598-4e79-9aeb-b0a9317e3433SPL ID d5427bbc-8598-4e79-9aeb-b0a9317e3433SPL set ID 54f01988-aac2-4b0e-9d20-b7f621a0cd50RxCUI 1720760UNII 778XL6VBS8
Pharmacologic class: Folate Analog

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N400143955801 followed by a unit qualifier and the quantity

Package 00143-9558-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Apr 7, 2021.

Indications (excerpt from the label)

Levoleucovorin for Injection is indicated for: rescue after high-dose methotrexate therapy in adult and pediatric patients with osteosarcoma. diminishing the toxicity associated with overdosage of folic acid antagonists or impaired methotrexate elimination in adult and pediatric patients. the treatment of adults with metastatic colorectal cancer in combination with fluorouracil. Limitations of Use Levoleucovorin for Injection is not indicated for pernicious anemia and megaloblastic anemia secondary to the lack of vitamin B12, because of the risk of progression of neurologic manifestations despite hematologic remission. Levoleucovorin for Injection is a folate analog indicated for: Rescue aft…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 0143-9558

What is NDC 0143-9558?: 0143-9558 is the product NDC for Levoleucovorin, Levoleucovorin calcium 50 mg/5mL injection, powder, lyophilized, for solution, listed with the FDA by Hikma Pharmaceuticals USA Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Levoleucovorin.
What is the active ingredient?: Levoleucovorin calcium.
Who is the labeler?: Hikma Pharmaceuticals USA Inc., NDC labeler code 0143. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Levoleucovorin?: 6 other product NDCs are listed under this name. See all Levoleucovorin NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Levoleucovorin NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Levoleucovorinlevoleucovorin calcium	Levoleucovorin calcium 50 mg/5mL	Injection, Powder, Lyophilized, For solutionIntravenous	Meitheal Pharmaceuticals Inc	71288-104	—
Levoleucovorinlevoleucovorin calcium	Levoleucovorin calcium 10 mg/mL	Injection, SolutionIntravenous	Meitheal Pharmaceuticals Inc.	71288-105	71288-0105-1871288-0105-25
Levoleucovorin	Levoleucovorin calcium 175 mg/17.5mL	Injection, SolutionIntravenous	Dr.Reddy's Laboratories Inc	43598-771	43598-0771-11
Levoleucovorin	Levoleucovorin calcium 250 mg/25mL	Injection, SolutionIntravenous	Dr.Reddy's Laboratories Inc	43598-773	43598-0773-11
levoleucovorin	Levoleucovorin calcium 10 mg/mL	InjectionIntravenous	Gland Pharma Limited	68083-278	68083-0278-01
levoleucovorin	Levoleucovorin calcium 10 mg/mL	InjectionIntravenous	Gland Pharma Limited	68083-279	68083-0279-01