What is NDC 0280-0105?

0280-0105 is the product NDC for Aleve liquid gels (naproxen sodium), Naproxen sodium 220 mg/1 capsule, liquid filled, listed with the FDA by Bayer Healthcare LLC. It has 6 package NDCs, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Aleve liquid gels (Naproxen Sodium).

Bayer Healthcare LLC, NDC labeler code 0280. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Aleve liquid gels?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Aleve liquid gels NDC 0280-0105 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)0280-0105Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00280-0105Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
0280-0105-01	0028001050100280010501	120 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-01)Marketed from Jun 28, 2024
0280-0105-02	0028001050200280010502	160 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-02)Marketed from Dec 1, 2023
0280-0105-03	0028001050300280010503	20 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-03)Marketed from May 7, 2024
0280-0105-04	0028001050400280010504	50 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-04)Marketed from May 14, 2024
0280-0105-05	0028001050500280010505	80 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-05)Marketed from May 21, 2024
0280-0105-06	0028001050600280010506	80 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-06)Marketed from Jun 17, 2024

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Aleve liquid gels
Generic name (nonproprietary): naproxen sodium
Active ingredients: Naproxen sodium — 220 mg/1
Dosage form: Capsule, Liquid filled
Route: Oral
Labeler: Bayer Healthcare LLCNDC labeler code 0280
Product type: Over-the-counter drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 214463
Marketing start: Dec 1, 2023
Listing expires: Dec 31, 2027
Other FDA classes: Non-Steroidal (Chemical structure)Cyclooxygenase Inhibitors (Mechanism)
Identifiers: Product ID 0280-0105_2766b060-5c1b-41fb-b8ca-cfb1a021b64eSPL ID 2766b060-5c1b-41fb-b8ca-cfb1a021b64eSPL set ID a0587c73-d297-462d-a0ef-750cb324486eRxCUI 1112231, 1112233UNII 9TN87S3A3C
Pharmacologic class: Nonsteroidal Anti-inflammatory Drug

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400280010501 followed by a unit qualifier and the quantity

Package 00280-0105-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective May 6, 2024.

Indications (excerpt from the label)

Uses temporarily relieves minor aches and pains due to: minor pain of arthritis muscular aches backache menstrual cramps headache toothache the common cold temporarily reduces fever

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 0280-0105

What is NDC 0280-0105?: 0280-0105 is the product NDC for Aleve liquid gels (naproxen sodium), Naproxen sodium 220 mg/1 capsule, liquid filled, listed with the FDA by Bayer Healthcare LLC. It has 6 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Aleve liquid gels (Naproxen Sodium).
What is the active ingredient?: Naproxen sodium.
Who is the labeler?: Bayer Healthcare LLC, NDC labeler code 0280. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Aleve liquid gels?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Aleve liquid gels (Naproxen sodium) NDC 0280-0105