What is NDC 0299-4908?

0299-4908 is the product NDC for Differin Epiduo, Adapalene 1 mg/g; Benzoyl peroxide 25 mg/g gel, listed with the FDA by Galderma Laboratories, L.P.. It has 3 package NDCs, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Differin Epiduo (Adapalene and Benzoyl Peroxide).

Galderma Laboratories, L.P., NDC labeler code 0299. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Differin Epiduo?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Differin Epiduo NDC 0299-4908 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)0299-4908Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00299-4908Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
0299-4908-00	0029949080000299490800	2 g in 1 TUBE (0299-4908-00)Marketed from May 22, 2026 · Sample package
0299-4908-10	0029949081000299490810	1 BOTTLE, PUMP in 1 CARTON (0299-4908-10) / 15 g in 1 BOTTLE, PUMPMarketed from May 22, 2026
0299-4908-40	0029949084000299490840	1 BOTTLE, PUMP in 1 CARTON (0299-4908-40) / 45 g in 1 BOTTLE, PUMPMarketed from May 22, 2026

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Differin Epiduo
Generic name (nonproprietary): adapalene and benzoyl peroxide
Active ingredients: Adapalene — 1 mg/gBenzoyl peroxide — 25 mg/g
Dosage form: Gel
Route: Topical
Labeler: Galderma Laboratories, L.P.NDC labeler code 0299
Product type: Over-the-counter drug
Marketing category: NDA — New Drug ApplicationApplication NDA 220736
Marketing start: May 22, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Retinoids (Chemical structure)
Identifiers: Product ID 0299-4908_30e41f9e-c736-40e3-bb96-df21c26d23fcSPL ID 30e41f9e-c736-40e3-bb96-df21c26d23fcSPL set ID ae3f8cd9-9046-4b69-b80f-3e9d4468ba7fRxCUI 829539, 2743622UNII 1L4806J2QF, W9WZN9A0GM
Pharmacologic class: Retinoid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400299490800 followed by a unit qualifier and the quantity

Package 00299-4908-00. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective May 20, 2026.

Indications (excerpt from the label)

Use For the treatment of acne

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 0299-4908

What is NDC 0299-4908?: 0299-4908 is the product NDC for Differin Epiduo, Adapalene 1 mg/g; Benzoyl peroxide 25 mg/g gel, listed with the FDA by Galderma Laboratories, L.P.. It has 3 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Differin Epiduo (Adapalene and Benzoyl Peroxide).
What is the active ingredient?: Adapalene, Benzoyl peroxide.
Who is the labeler?: Galderma Laboratories, L.P., NDC labeler code 0299. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Differin Epiduo?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Differin Epiduo (Adapalene and benzoyl peroxide) NDC 0299-4908