NDC codes

FDA NDC Directory
Product NDC (as listed)0409-3365Labeler and product segments. Claims need a package NDC.
Product NDC at billing width00409-3365Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
0409-3365-100040933651010 VIAL, SINGLE-DOSE in 1 CARTON (0409-3365-10) / 1 mL in 1 VIAL, SINGLE-DOSE (0409-3365-11)Marketed from Jun 14, 2021

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Hydromorphone Hydrochloride
Generic name (nonproprietary)
hydromorphone hydrochloride
Active ingredients
Hydromorphone hydrochloride — 2 mg/mL
Dosage form
Injection, Solution
Route
Intramuscular, Intravenous, Subcutaneous
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 200403
Marketing start
Listing expires
DEA schedule
CII
Other FDA classes
Full Opioid Agonists (Mechanism)
Identifiers
Product ID 0409-3365_a3ebafac-648e-47b1-a6f5-1e3bff1e3e08SPL ID a3ebafac-648e-47b1-a6f5-1e3bff1e3e08SPL set ID e9c9ef18-7dfc-4322-b2fc-29b934c30f8bRxCUI 897653, 897753, 897756, 897757, 897758, 1724276, 1724383, 1724644UNII L960UP2KRW
Pharmacologic class
Opioid Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N400409336510 followed by a unit qualifier and the quantity

Package 00409-3365-10. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

Hydromorphone Hydrochloride Injection is indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Hydromorphone Hydrochloride Injection is an opioid agonist indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. ( 1 ) Limitations of Use: Because of the risks of addiction, abuse, misuse, overdose, and death, which can occur at any dosage or duration and persist over the course of therapy, reserve opioid analgesics, including Hydromorphone Hydrochloride Injection, for use in patients for whom alternative treatment options are ineffective,…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 200403

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 200403
ProductStrengthForm · routeLabelerProduct NDC
Hydromorphone HydrochlorideHydromorphone hydrochloride 1 mg/mLInjection, SolutionIntramuscular, Intravenous, SubcutaneousHospira, Inc.0409-1283
Hydromorphone HydrochlorideHydromorphone hydrochloride .25 mg/.5mLInjection, SolutionIntramuscular, Intravenous, SubcutaneousHospira, Inc.0409-1805
Hydromorphone HydrochlorideHydromorphone hydrochloride 1 mg/mLInjection, SolutionIntramuscular, Intravenous, SubcutaneousHospira, Inc.0409-1283
Hydromorphone HydrochlorideHydromorphone hydrochloride 4 mg/mLInjection, SolutionIntramuscular, Intravenous, SubcutaneousHospira, Inc.0409-1304
Hydromorphone HydrochlorideHydromorphone hydrochloride 2 mg/mLInjection, SolutionIntramuscular, Intravenous, SubcutaneousHospira, Inc.0409-1312
Hydromorphone HydrochlorideHydromorphone hydrochloride 2 mg/mLInjection, SolutionIntramuscular, Intravenous, SubcutaneousHospira, Inc.0409-1312
Hydromorphone HydrochlorideHydromorphone hydrochloride .5 mg/.5mLInjection, SolutionIntramuscular, Intravenous, SubcutaneousHospira, Inc.0409-4264

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