What is NDC 0456-1228?

0456-1228 is the product NDC for Namzaric, Memantine hydrochloride 28 mg/1; Donepezil hydrochloride 10 mg/1 capsule, listed with the FDA by Allergan, Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Namzaric (Memantine hydrochloride and donepezil hydrochloride).

What is the active ingredient?

Memantine hydrochloride, Donepezil hydrochloride.

Allergan, Inc., NDC labeler code 0456. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Namzaric?

3 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Namzaric NDC 0456-1228 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)0456-1228Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00456-1228Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
0456-1228-30	0045612283000456122830	30 CAPSULE in 1 BOTTLE (0456-1228-30)Marketed from Dec 24, 2014

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Namzaric
Generic name (nonproprietary): memantine hydrochloride and donepezil hydrochloride
Active ingredients: Memantine hydrochloride — 28 mg/1Donepezil hydrochloride — 10 mg/1
Dosage form: Capsule
Route: Oral
Labeler: Allergan, Inc.NDC labeler code 0456
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 206439
Marketing start: Dec 24, 2014
Listing expires: Dec 31, 2027
Other FDA classes: Cholinesterase Inhibitors (Mechanism)NMDA Receptor Antagonists (Mechanism)
Identifiers: Product ID 0456-1228_00cae29c-d07a-484b-b279-be68f15c5e73SPL ID 00cae29c-d07a-484b-b279-be68f15c5e73SPL set ID 90fedc32-19e5-480c-afc6-f35a5cf4b9aaRxCUI 1599803, 1599805, 1602588, 1602594, 1805420, 1805422, 1805425, 1805427, 1858970, 1858971UNII 3O2T2PJ89D, JY0WD0UA60UPC 0304561221301, 0304561207305
Pharmacologic class: Cholinesterase Inhibitor; N-methyl-D-aspartate Receptor Antagonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400456122830 followed by a unit qualifier and the quantity

Package 00456-1228-30. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Mar 6, 2026.

Indications (excerpt from the label)

NAMZARIC is indicated for the treatment of moderate to severe dementia of the Alzheimer’s type in patients stabilized on 10 mg of donepezil hydrochloride once daily. NAMZARIC is a combination of memantine hydrochloride, an NMDA receptor antagonist, and donepezil hydrochloride, an acetylcholinesterase inhibitor, indicated for the treatment of moderate to severe dementia of the Alzheimer’s type in patients stabilized on 10 mg of donepezil hydrochloride once daily. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 0456-1228

What is NDC 0456-1228?: 0456-1228 is the product NDC for Namzaric, Memantine hydrochloride 28 mg/1; Donepezil hydrochloride 10 mg/1 capsule, listed with the FDA by Allergan, Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Namzaric (Memantine hydrochloride and donepezil hydrochloride).
What is the active ingredient?: Memantine hydrochloride, Donepezil hydrochloride.
Who is the labeler?: Allergan, Inc., NDC labeler code 0456. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Namzaric?: 3 other product NDCs are listed under this name. See all Namzaric NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Namzaric NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Namzaricmemantine hydrochloride and donepezil hydrochloride	Memantine hydrochloride 7 mg/1; Donepezil hydrochloride 10 mg/1	CapsuleOral	Allergan, Inc.	0456-1207	00456-1207-30
Namzaricmemantine hydrochloride and donepezil hydrochloride	Memantine hydrochloride 21 mg/1; Donepezil hydrochloride 10 mg/1	CapsuleOral	Allergan, Inc.	0456-1221	00456-1221-30
Namzaricmemantine hydrochloride and donepezil hydrochloride	Memantine hydrochloride 14 mg/1; Donepezil hydrochloride 10 mg/1	CapsuleOral	Allergan, Inc.	0456-1214	00456-1214-30

Other NDCs under NDA 206439

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 206439
Product	Strength	Form · route	Labeler	Product NDC
Namzaricmemantine hydrochloride and donepezil hydrochloride	Memantine hydrochloride 7 mg/1; Donepezil hydrochloride 10 mg/1	CapsuleOral	Allergan, Inc.	0456-1207
Namzaricmemantine hydrochloride and donepezil hydrochloride	Memantine hydrochloride 14 mg/1; Donepezil hydrochloride 10 mg/1	CapsuleOral	Allergan, Inc.	0456-1214
Namzaricmemantine hydrochloride and donepezil hydrochloride	Memantine hydrochloride 21 mg/1; Donepezil hydrochloride 10 mg/1	CapsuleOral	Allergan, Inc.	0456-1221