Dopram (doxapram hydrochloride) NDC 0641-6018

NDC codes

FDA NDC Directory

Product NDC (as listed)0641-6018Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00641-6018Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
0641-6018-01	00641601801	20 mL in 1 VIAL (0641-6018-01)Marketed from Jun 23, 1965
0641-6018-06	00641601806	6 VIAL in 1 CARTON (0641-6018-06) / 20 mL in 1 VIAL (0641-6018-01)Marketed from Jun 23, 1965

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Dopram
Generic name (nonproprietary): doxapram hydrochloride
Active ingredients: Doxapram hydrochloride — 20 mg/mL
Dosage form: Injection
Route: Intravenous
Labeler: Hikma Pharmaceuticals USA Inc.
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 014879
Marketing start: Jun 23, 1965
Listing expires: Dec 31, 2026
Other FDA classes: Increased Medullary Respiratory Drive (Physiologic effect)
Identifiers: Product ID 0641-6018_ccb9f1b7-b7b1-4db2-b5db-093d147529a7SPL ID ccb9f1b7-b7b1-4db2-b5db-093d147529a7SPL set ID b8eb330a-a75b-46cb-b694-5be9327ed2ebRxCUI 1047087, 1047511UNII P5RU6UOQ5Y
Pharmacologic class: Respiratory Stimulant

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N400641601801 followed by a unit qualifier and the quantity

Package 00641-6018-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Apr 9, 2024.

Indications (excerpt from the label)

INDICATIONS AND USAGE Postanesthesia When the possibility of airway obstruction and/or hypoxia have been eliminated, doxapram may be used to stimulate respiration in patients with drug-induced postanesthesia respiratory depression or apnea other than that due to muscle relaxant drugs. To pharmacologically stimulate deep breathing in the postoperative patient. (A quantitative method of assessing oxygenation, such as pulse oximetry, is recommended.) Drug-Induced Central Nervous System Depression Exercising care to prevent vomiting and aspiration, doxapram may be used to stimulate respiration, hasten arousal, and to encourage the return of laryngopharyngeal reflexes in patients with mild to mod…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 014879

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 014879
Product	Strength	Form · route	Labeler	Product NDC
Doxapram Hydrochloride	Doxapram hydrochloride 20 mg/mL	InjectionIntravenous	HF Acquisition Co LLC, DBA HealthFirst	51662-1404