What is NDC 14222-2111?

14222-2111 is the product NDC for UNBLEMISH Refining Acne Wash (salicylic acid), Salicylic acid .005 g/mL cream, listed with the FDA by Rodan & Fields. It has 3 package NDCs, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

UNBLEMISH Refining Acne Wash (Salicylic acid).

Rodan & Fields, NDC labeler code 14222. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for UNBLEMISH Refining Acne Wash?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

UNBLEMISH Refining Acne Wash NDC 14222-2111

NDC codes

FDA NDC Directory

Product NDC (as listed)14222-2111Labeler and product segments. Claims need a package NDC.

Product NDC at billing width14222-2111Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
14222-2111-1	1422221110114222211101	1 TUBE in 1 CARTON (14222-2111-1) / 125 mL in 1 TUBEMarketed from Mar 10, 2020
14222-2111-2	1422221110214222211102	1 TUBE in 1 CARTON (14222-2111-2) / 30 mL in 1 TUBEMarketed from Jun 1, 2020
14222-2111-3	1422221110314222211103	2 mL in 1 PACKET (14222-2111-3)Marketed from Apr 12, 2022

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): UNBLEMISH Refining Acne Wash
Generic name (nonproprietary): salicylic acid
Active ingredients: Salicylic acid — .005 g/mL
Dosage form: Cream
Route: Topical
Labeler: Rodan & FieldsNDC labeler code 14222
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 006
Marketing start: Mar 10, 2020
Listing expires: Dec 31, 2027
Identifiers: Product ID 14222-2111_132a70aa-7ab9-4b3f-9e75-612267934dabSPL ID 132a70aa-7ab9-4b3f-9e75-612267934dabSPL set ID 08922efa-5a90-4dfb-b9f4-a6c4f8dba3c9RxCUI 865105UNII O414PZ4LPZUPC 0884164014468

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N414222211101 followed by a unit qualifier and the quantity

Package 14222-2111-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Mar 31, 2026.

Indications (excerpt from the label)

Uses for the treatment of acne helps keep skin clear of new acne blemishes, acne pimples, blackheads and whiteheads

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 14222-2111

What is NDC 14222-2111?: 14222-2111 is the product NDC for UNBLEMISH Refining Acne Wash (salicylic acid), Salicylic acid .005 g/mL cream, listed with the FDA by Rodan & Fields. It has 3 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: UNBLEMISH Refining Acne Wash (Salicylic acid).
What is the active ingredient?: Salicylic acid.
Who is the labeler?: Rodan & Fields, NDC labeler code 14222. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for UNBLEMISH Refining Acne Wash?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other NDCs under M 006

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 006
Product	Strength	Form · route	Labeler	Product NDC
UNBLEMISH Dual Intensive Acne Treatmentbenzoyl peroxide	Benzoyl peroxide .025 g/mL	LotionTopical	Rodan & Fields	14222-2120
Dr. Dennis Gross Alpha Beta On the Spot Eliminatorsalicylic acid	Salicylic acid 20 mg/mL	GelTopical	Topiderm, Inc	51326-057
The INKEY List Salicylic Acid Cleansersalicylic acid	Salicylic acid 20 mg/mL	GelTopical	Brand Evangelists for Beauty Ltd	81136-019
Anubis Barcelonapeg-40 hydrogenated castor oil, propylene glycol, allantoin	Propylparaben .0000001 g/5mL + 26 more ingredients	ConcentrateTopical	ANUBIS COSMETICS SL	83021-617
CAVOREAL Plus Salicylic Acid Anti Acne with BHA HAsalicylic acid	Salicylic acid 1 g/15g	CreamTransdermal	Guangzhou Meijiao Medical Biotechnology Co., Ltd.	87036-033
Perricone MD Acne Relief Gentle Exfoliating Toner Salicylic Acid Acne Treatmentsalicylic acid	Salicylic acid 2 g/100mL	LiquidTopical	THG Beauty USA LLC	84448-602
Sylvirene Milia Removersalicylic acid 1% milia remover	Salicylic acid 1 g/100mL	LiquidTopical	Jiangxi Yudexi Pharmaceutical Co., LTD	85248-071
Proactiv Emergency Blemish Reliefbenzoyl peroxide	Benzoyl peroxide 5 g/100g	CreamTopical	Alchemee, LLC	11410-012
Proactiv Clean Mineral Acne Cleansersulfur	Sulfur 3 g/100mL	CreamTopical	Alchemee, LLC	11410-457
BP Washbenzoyl peroxide	Benzoyl peroxide 25 mg/g	EmulsionTopical	CINTEX SERVICES, LLC	24470-911
Differin Max Strength Acne Foaming BPO Cleanserbenzoyl peroxide	Benzoyl peroxide 10 g/100mL	SolutionTopical	Galderma Laboratories, L.P.	0299-4137
Perricone MD Acne Relief Gentle and Soothing Cleansersalicylic acid	Salicylic acid 2 g/100mL	GelTopical	THG Beauty USA LLC	84448-539
Gly-Sal 5-2 Padssalicylic acid	Salicylic acid .02 g/1	ClothTopical	Topiderm, Inc.	51326-038
Gly-Sal 10-2 Padssalicylic acid	Salicylic acid .02 g/1	ClothTopical	Topiderm, Inc.	51326-039
Clinicians Complexsulfur	Sulfur 100 mg/g	LotionTopical	SkinSx.com, Inc.	72622-001
Blemish Blitz Emergency Acne Serumsalicylic acid	Salicylic acid .01 g/mL	LiquidTopical	Guangdong Joyan Biological Technology Co.,Ltd	85779-003
CAVOREAL Plus Salicylic Acid Anti Acne with BHA HAsalicylic acid	Salicylic acid 1 g/15mL	CreamTransdermal	Guangzhou Meijiao Medical Biotechnology Co., Ltd.	87036-032
Perricone MD Acne Relief Calming Treatment and Hydrator Salicylic Acid Acne Treatmentsalicylic acid	Salicylic acid .5 g/100mL	CreamTopical	THG Beauty USA LLC	84448-540
Oxy Sensitive Skin Acne Cleansing Padssalicylic acid 0.5%	Salicylic acid 5 mg/1	ClothTopical	The Mentholatum Company	10742-1007
Oxy Total Care Clarifying Moisturizerbenzoyl peroxide	Benzoyl peroxide 25 mg/mL	LotionTopical	The Mentholatum Company	10742-1314

Showing 20 of 39.

UNBLEMISH Refining Acne Wash (Salicylic acid) NDC 14222-2111