What is NDC 14222-2420?

14222-2420 is the product NDC for SOOTHE Sensitive Skin Treatment, Allantoin .5 g/100mL; Dimethicone 2 g/100mL lotion, listed with the FDA by Rodan & Fields. It has 3 package NDCs, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

SOOTHE Sensitive Skin Treatment (Allantoin, Dimethicone).

Rodan & Fields, NDC labeler code 14222. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for SOOTHE Sensitive Skin Treatment?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

SOOTHE Sensitive Skin Treatment NDC 14222-2420

NDC codes

FDA NDC Directory

Product NDC (as listed)14222-2420Labeler and product segments. Claims need a package NDC.

Product NDC at billing width14222-2420Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
14222-2420-1	1422224200114222242001	1 BOTTLE in 1 CARTON (14222-2420-1) / 50 mL in 1 BOTTLEMarketed from Mar 9, 2021
14222-2420-2	1422224200214222242002	1 TUBE in 1 CARTON (14222-2420-2) / 10 mL in 1 TUBEMarketed from Jun 1, 2021
14222-2420-3	1422224200314222242003	2 mL in 1 PACKET (14222-2420-3)Marketed from Apr 12, 2022

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): SOOTHE Sensitive Skin Treatment
Generic name (nonproprietary): allantoin, dimethicone
Active ingredients: Allantoin — .5 g/100mLDimethicone — 2 g/100mL
Dosage form: Lotion
Route: Topical
Labeler: Rodan & FieldsNDC labeler code 14222
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 016
Marketing start: Mar 9, 2021
Listing expires: Dec 31, 2026
Other FDA classes: Skin Barrier Activity (Physiologic effect)
Identifiers: Product ID 14222-2420_bbb80b31-6ecc-4d23-a2c3-784c6ea2289cSPL ID bbb80b31-6ecc-4d23-a2c3-784c6ea2289cSPL set ID 2bd8cac4-5f40-4d04-91f2-3ea8a138033bUNII 344S277G0Z, 92RU3N3Y1OUPC 0884164014208

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N414222242001 followed by a unit qualifier and the quantity

Package 14222-2420-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Dec 9, 2024.

Indications (excerpt from the label)

Uses Temporarily protects and helps relieve chapped or cracked skin. Helps protect from the drying effects of wind and cold weather.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 14222-2420

What is NDC 14222-2420?: 14222-2420 is the product NDC for SOOTHE Sensitive Skin Treatment, Allantoin .5 g/100mL; Dimethicone 2 g/100mL lotion, listed with the FDA by Rodan & Fields. It has 3 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: SOOTHE Sensitive Skin Treatment (Allantoin, Dimethicone).
What is the active ingredient?: Allantoin, Dimethicone.
Who is the labeler?: Rodan & Fields, NDC labeler code 14222. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for SOOTHE Sensitive Skin Treatment?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other NDCs under M 016

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 016
Product	Strength	Form · route	Labeler	Product NDC
2-Pack Facial Serum	Water 78.894 g/100mL + 4 more ingredients	LiquidCutaneous	Guangzhou Ariel Biotech Co., Ltd.	84148-011
2-Pack Facial Serum	3-o-ethyl ascorbic acid .5 g/100mL + 3 more ingredients	LiquidCutaneous	Guangzhou Ariel Biotech Co., Ltd.	84148-012
3M Cavilon Durable Barrierdimethicone	Dimethicone 13000 mg/L	CreamTopical	Solventum US LLC	17518-030
4% 10gTATTOO Numb Cream4% lidocaine	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-031
4% TATTOO Numb Cream4% lidocaine	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-030
456 Acne Relief Creamniacinamide,salicylic acid,centella asiatica root,coptis chinensis root	Salicylic acid 380 mg/50g + 3 more ingredients	CreamTopical	Guangzhou Senmai Biotechnology Co.,Ltd.	84509-111
5% Dr.care Numb creamlidocaine	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-028
5% Minoxidil	Minoxidil 2 g/100g + 3 more ingredients	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-328
5% Minoxidil	Minoxidil 2 g/100g + 3 more ingredients	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-329
5% Minoxidil	Biotin .05 g/100g; Niacinamide 2.5 g/100g	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-335
5% Minoxidil	Minoxidil 5 g/100g + 5 more ingredients	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-337
5% Minoxidil for Men and Women	Biotin .05 g/100g; Tocopherol .05 g/100g	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-332
5% Minoxidil Hair Growth	Biotin .1 g/100g + 3 more ingredients	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-333
5% Minoxidil Hair Growth	Minoxidil 5 g/100g + 3 more ingredients	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-334
5% Signature Numb creamlidocaine	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-026
5% Signature Numb cream5% signature	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-027
5% Signature Numb cream5% lidocaine	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-029
70% Isopropyl Rubbing Alcoholisopropyl alcohol	Isopropyl alcohol 70 mL/100mL	LiquidTopical	MY IMPORTS USA LLC	51628-4501
911allantoin	Allantoin .5 g/100g	OintmentTopical	Skinfix, Inc.	61328-120
A and Dpetrolatum	Petrolatum 76 g/100g	OintmentTopical	Safetec of America, Inc.	61010-4405

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SOOTHE Sensitive Skin Treatment (Allantoin, dimethicone) NDC 14222-2420