EstroGel (estradiol) NDC 17139-617

NDC codes

FDA NDC Directory

Product NDC (as listed)17139-617Labeler and product segments. Claims need a package NDC.

Product NDC at billing width17139-0617Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
17139-617-40	17139061740	50 g in 1 BOTTLE, PUMP (17139-617-40)Marketed from Feb 9, 2004

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): EstroGel
Generic name (nonproprietary): estradiol
Active ingredients: Estradiol — .75 mg/1.25g
Dosage form: Gel, Metered
Route: Topical
Labeler: ASCEND Therapeutics US, LLC
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 021166
Marketing start: Feb 9, 2004
Listing expires: Dec 31, 2027
Other FDA classes: Estradiol Congeners (Chemical structure)Estrogen Receptor Agonists (Mechanism)
Identifiers: Product ID 17139-617_55240d4b-c38e-43ed-9d58-a9f5d453d2c2SPL ID 55240d4b-c38e-43ed-9d58-a9f5d453d2c2SPL set ID 762ac371-bb8b-47e7-b48f-e80d452c9dd4RxCUI 226597, 581549UNII 4TI98Z838EUPC 0317139617406
Pharmacologic class: Estrogen

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N417139061740 followed by a unit qualifier and the quantity

Package 17139-0617-40. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective May 29, 2026. This label includes a boxed warning.

Indications (excerpt from the label)

EstroGel 0.06% is an estrogen indicated for: Treatment of moderate to severe vasomotor symptoms due to menopause ( 1.1 ) Treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to menopause ( 1.2 ) 1.1 Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause. 1.2 Treatment of Moderate to Severe Symptoms of Vulvar and Vaginal Atrophy due to Menopause. Limitation of Use When prescribing solely for the treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to menopause, first consider the use of topical vaginal products.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)