What is NDC 21130-754?

21130-754 is the product NDC for Adapalene, Adapalene 1 mg/g gel, listed with the FDA by Safeway, Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.

Safeway, Inc., NDC labeler code 21130. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Adapalene?

35 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Adapalene NDC 21130-754 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)21130-754Labeler and product segments. Claims need a package NDC.

Product NDC at billing width21130-0754Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
21130-754-05	2113007540521130075405	1 TUBE in 1 CARTON (21130-754-05) / 15 g in 1 TUBEMarketed from Jan 31, 2024

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Adapalene
Generic name (nonproprietary): adapalene
Active ingredients: Adapalene — 1 mg/g
Dosage form: Gel
Route: Topical
Labeler: Safeway, Inc.NDC labeler code 21130
Product type: Over-the-counter drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 090962
Marketing start: Jan 31, 2024
Listing expires: Dec 31, 2027
Other FDA classes: Retinoids (Chemical structure)
Identifiers: Product ID 21130-754_d22d813a-9035-4065-9f49-51b778527c72SPL ID d22d813a-9035-4065-9f49-51b778527c72SPL set ID a9816181-d643-4579-8b12-3927120dc627RxCUI 307731UNII 1L4806J2QFUPC 0321130129318
Pharmacologic class: Retinoid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N421130075405 followed by a unit qualifier and the quantity

Package 21130-0754-05. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jun 18, 2026.

Indications (excerpt from the label)

Use For the treatment of acne

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 21130-754

What is NDC 21130-754?: 21130-754 is the product NDC for Adapalene, Adapalene 1 mg/g gel, listed with the FDA by Safeway, Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Adapalene.
What is the active ingredient?: Adapalene.
Who is the labeler?: Safeway, Inc., NDC labeler code 21130. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Adapalene?: 35 other product NDCs are listed under this name. See all Adapalene NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Adapalene NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Adapalene	Adapalene 1 mg/g	GelTopical	YYBA Corp	73581-216	73581-0216-45
Adapalene	Adapalene 1 mg/g	GelTopical	YYBA CORP	73581-215	73581-0215-45
Adapalene	Adapalene 1 mg/g	GelTopical	Walgreens	0363-4110	00363-4110-0500363-4110-16
Adapalene	Adapalene 1 mg/g	GelTopical	Wal-Mart Stores Inc	79903-338	79903-0338-05
Adapalene	Adapalene 3 mg/g	GelTopical	Alembic Pharmaceuticals Limited	46708-549	46708-0549-1546708-0549-4546708-0549-46
Adapalene	Adapalene 1 mg/g	GelTopical	YYBA Corp	73581-019	73581-0019-06
Adapalene	Adapalene 1 mg/g	GelTopical	Target Corporation	82442-105	82442-0105-01
Adapalene	Adapalene 1 mg/g	GelTopical	RITE AID	11822-0062	11822-0062-01
Adapalene	Adapalene 1 mg/g	GelTopical	Cardinal Health	70000-0666	70000-0666-0170000-0666-02
Adapalene	Adapalene 1 mg/g	GelTopical	The Kroger Co.	30142-725	30142-0725-05

All 36 Adapalene NDCs

Other NDCs under ANDA 090962

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 090962
Product	Strength	Form · route	Labeler	Product NDC
Adapalene	Adapalene 1 mg/g	GelTopical	Walgreens	0363-1401
Adapalene	Adapalene 1 mg/g	GelTopical	Walgreens	0363-4110
Adapalene	Adapalene 1 mg/g	GelTopical	The Kroger Co.	30142-725
Adapalene	Adapalene 1 mg/g	GelTopical	CVS PHARMACY, INC	51316-114
Adapalene	Adapalene 1 mg/g	GelTopical	P & L Development, LLC	59726-114
Adapalene	Adapalene 1 mg/g	GelTopical	YYBA CORP	73581-215
Adapalene	Adapalene 1 mg/g	GelTopical	Topco Associates	76162-114
Adapalene	Adapalene 1 mg/g	GelTopical	Meijer Distribution Inc.	79481-1140
Adapalene Paraben Freeadapalene	Adapalene 1 mg/g	GelTopical	The Kroger Co.	30142-542
Adapalene Paraben Freeadapalene	Adapalene 1 mg/g	GelTopical	CVS PHARMACY, INC	51316-219
Adapalene Paraben Freeadapalene	Adapalene 1 mg/g	GelTopical	Topco Associates	76162-221
Adapalene Paraben Freeadapalene	Adapalene 1 mg/g	GelTopical	Meijer Distribution Inc.	79481-2210
Neutrogena Adapalene 0.1% Acne Treatmentadapalene	Adapalene 1 mg/g	GelTopical	Kenvue Brands LLC	69968-0826
Neutrogena Evenly Clear Retinoid Adapalene Gel 0.1% Acne Treatmentadapalene	Adapalene 1 mg/g	GelTopical	Kenvue Brands LLC	69968-0945
Neutrogena Evenly Clear Retinoid Adapalene Gel 0.1% Acne Treatmentadapalene	Adapalene 1 mg/g	GelTopical	Kenvue Brands LLC	69968-1004