What is NDC 21130-789?

21130-789 is the product NDC for Signature Care Hemorrhoidal, Petrolatum 749 mg/g + 2 more ingredients ointment, listed with the FDA by Better Living Brands, LLC. It has 1 package NDC, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Signature Care Hemorrhoidal (Mineral oil, Petrolatum, and Phenylephrine HCI).

What is the active ingredient?

Petrolatum, Phenylephrine hydrochloride, Mineral oil.

Better Living Brands, LLC, NDC labeler code 21130. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Signature Care Hemorrhoidal?

2 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Signature Care Hemorrhoidal NDC 21130-789

NDC codes

FDA NDC Directory

Product NDC (as listed)21130-789Labeler and product segments. Claims need a package NDC.

Product NDC at billing width21130-0789Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
21130-789-14	2113007891421130078914	1 TUBE in 1 CARTON (21130-789-14) / 28 g in 1 TUBEMarketed from Jan 21, 2016

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Signature Care Hemorrhoidal
Generic name (nonproprietary): mineral oil, petrolatum, and phenylephrine hci
Active ingredients: Petrolatum — 749 mg/gPhenylephrine hydrochloride — 2.5 mg/gMineral oil — 140 mg/g
Dosage form: Ointment
Route: Topical
Labeler: Better Living Brands, LLCNDC labeler code 21130
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 015
Marketing start: Jan 20, 2016
Listing expires: Dec 31, 2027
Other FDA classes: Adrenergic alpha1-Agonists (Mechanism)
Identifiers: Product ID 21130-789_4a197084-aa10-02ef-e063-6394a90a1e46SPL ID 4a197084-aa10-02ef-e063-6394a90a1e46SPL set ID 3c8b43f3-6e1e-499e-ba71-ffdf836f6743RxCUI 1372298UNII 4T6H12BN9U, 04JA59TNSJ, T5L8T28FGPUPC 0321130789826
Pharmacologic class: alpha-1 Adrenergic Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N421130078914 followed by a unit qualifier and the quantity

Package 21130-0789-14. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Feb 5, 2026.

Indications (excerpt from the label)

Directions adults: when practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe. Gently dry by patting or blotting with a tissue or a soft cloth before applying ointment. when first opening the tube, puncture foil seal with top end of cap apply to the affected area up to 4 times daily, especially at night, in the morning or after each bowel movement interacetal use: remove cover from applicator, attach applicator to tube, lubricate applicator well and gently insert applicator into thoroughly cleanse applicator after each use and replace cover also apply ointment to external area regular use provides continual therapy for relief of symptoms children unde…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 21130-789

What is NDC 21130-789?: 21130-789 is the product NDC for Signature Care Hemorrhoidal, Petrolatum 749 mg/g + 2 more ingredients ointment, listed with the FDA by Better Living Brands, LLC. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Signature Care Hemorrhoidal (Mineral oil, Petrolatum, and Phenylephrine HCI).
What is the active ingredient?: Petrolatum, Phenylephrine hydrochloride, Mineral oil.
Who is the labeler?: Better Living Brands, LLC, NDC labeler code 21130. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Signature Care Hemorrhoidal?: 2 other product NDCs are listed under this name. See all Signature Care Hemorrhoidal NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Signature Care Hemorrhoidal NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
signature care hemorrhoidalmineral oil, petrolatum, phenylephrine hcl	Mineral oil 14 g/100g + 2 more ingredients	OintmentRectal	Safeway	21130-577	21130-0577-16
Signature Care Hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	Safeway	21130-628	21130-0628-62

Other NDCs under M 015

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 015
Product	Strength	Form · route	Labeler	Product NDC
Pramoxine Hydrochloride Anorectalpramoxine hydrochloride	Pramoxine hydrochloride 1 mg/mL	LotionTopical	Stratus Pharmaceuticals	58980-522
Ma Ying Long Musk Hemorrhoidspetrolatum, zinc oxide	Petrolatum 779.9 mg/g; Zinc oxide 76 mg/g	OintmentTopical	Mayinglong Pharmaceutical Group Co., Ltd.	68511-997
Mayinglong Hemorrhoidalpetrolatum, zinc oxide	Petrolatum 779.9 mg/g; Zinc oxide 76 mg/g	OintmentTopical	Mayinglong Pharmaceutical Group Co., Ltd.	68511-998
hemorrhoidal maximum strength pain reliefglycerin, phenylephrine hcl, pramoxine hcl, white petrolatum	Glycerin 14.4 g/100g + 3 more ingredients	CreamTopical	Kroger Company	30142-944
Preparation Hcocoa butter, phenylephrine hydrochloride, and witch hazel	—	Kit	Haleon US Holdings LLC	0573-2884
Hemorrhoidalmineral oil, petrolatum, phenylephrine hcl	Mineral oil 14 g/100g + 2 more ingredients	OintmentRectal	Kroger Company	30142-188
rexall hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	Dolgencorp Inc	55910-279
Witch Hazel	Witch hazel 860 mg/mL	LiquidTopical	CVS Pharmacy, Inc.	59779-045
Dermatool Hemorrhoidalglycerin, lidocaine, petrolatum, phenylephrine hcl	Lidocaine 5 g/100g + 3 more ingredients	CreamTopical	Papalo Group LLC	84728-413
Acolye Numbing Cream Anorectal(Hemorrhoidal) Creamlidocaine	Lidocaine 5 g/100g	CreamTopical	Guangzhou Haishi Biological Technology Co., Ltd.	60771-0028
Hemorrhoid Anestheticmineral oil, petrolatum, phenylephrine hcl	Petrolatum .749 g/g + 2 more ingredients	OintmentTopical	Savvy Care and Cosmetics	83650-110
hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	Meijer Distribution Inc	41250-279
Lidocaine Numbing Creamlidocaine	Lidocaine .05 g/g	CreamTopical	Shanghai Chuangshi Medical Technology (Group) Co., Ltd.	73557-311
RWWXII Deep Numbing Cream(Anorectal Hemorrhoidal Cream)lidocaine	Lidocaine 5 g/100g	CreamTopical	Guangzhou Haishi Biological Technology Co., Ltd.	60771-0027
Barrier Protectant Creambarrier cream	Menthol 1 mg/g; Zinc oxide 200 mg/g	OintmentTopical	Cardinal Health	63517-003
ER Hemorrhoidphenylephrine hcl	Mineral oil .14 g/g + 2 more ingredients	CreamRectal	EVER READY FIRST AID	72976-018
ANIXIKE Numbinglidocaine4% numbing	Lidocaine 4 g/100g	CreamTopical	Jiangxi Yudexi Pharmaceutical Co., LTD	85248-166
Meijer Maximum strength pain relieving cleansingbenzalkonium chloride and lidocaine hydrochloride	Benzalkonium chloride .13 g/100mL; Lidocaine hydrochloride 4 g/100mL	LiquidTopical	MEIJER DISTRIBUTION, INC.	41250-287
hemorrhoidalglycerin, phenylephrine hcl, pramoxine hcl, white petrolatum	Glycerin 14.4 g/100g + 3 more ingredients	CreamTopical	Meijer Distribution Inc	41250-944
Equaline Hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	United Natural Foods, Inc. dba UNFI	41163-279

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