What is NDC 21922-054?

21922-054 is the product NDC for Nitroglycerin, Nitroglycerin 20 mg/g ointment, listed with the FDA by Encube Ethicals, Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.

Encube Ethicals, Inc., NDC labeler code 21922. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Nitroglycerin?

69 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Nitroglycerin NDC 21922-054 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)21922-054Labeler and product segments. Claims need a package NDC.

Product NDC at billing width21922-0054Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
21922-054-05	2192200540521922005405	1 TUBE in 1 CARTON (21922-054-05) / 30 g in 1 TUBEMarketed from Apr 16, 2025
21922-054-47	2192200544721922005447	48 POUCH in 1 CARTON (21922-054-47) / 1 g in 1 POUCH (21922-054-59)Marketed from Apr 16, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Nitroglycerin
Generic name (nonproprietary): nitroglycerin
Active ingredients: Nitroglycerin — 20 mg/g
Dosage form: Ointment
Route: Topical
Labeler: Encube Ethicals, Inc.NDC labeler code 21922
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 218235
Marketing start: Apr 16, 2025
Listing expires: Dec 31, 2027
Other FDA classes: Nitrates (Chemical structure)Vasodilation (Physiologic effect)
Identifiers: Product ID 21922-054_a46f7681-b936-40d3-8c36-e9bb5d655d73SPL ID a46f7681-b936-40d3-8c36-e9bb5d655d73SPL set ID c17c997b-0e90-4105-888b-2de22d2bf697RxCUI 242946UNII G59M7S0WS3UPC 0321922054057, 0321922054477
Pharmacologic class: Nitrate Vasodilator

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N421922005405 followed by a unit qualifier and the quantity

Package 21922-0054-05. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective May 28, 2026.

Indications (excerpt from the label)

INDICATIONS AND USAGE Nitroglycerin ointment USP, 2% is indicated for the prevention of angina pectoris due to coronary artery disease. The onset of action of transdermal nitroglycerin is not sufficiently rapid for this product to be useful in aborting an acute anginal episode.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 21922-054

What is NDC 21922-054?: 21922-054 is the product NDC for Nitroglycerin, Nitroglycerin 20 mg/g ointment, listed with the FDA by Encube Ethicals, Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Nitroglycerin.
What is the active ingredient?: Nitroglycerin.
Who is the labeler?: Encube Ethicals, Inc., NDC labeler code 21922. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Nitroglycerin?: 69 other product NDCs are listed under this name. See all Nitroglycerin NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Nitroglycerin NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Nitroglycerin	Nitroglycerin 4 mg/g	OintmentRectal	Padagis Israel Pharmaceuticals Ltd	45802-932	45802-0932-94
Nitroglycerin	Nitroglycerin 4 mg/g	OintmentRectal	Bryant Ranch Prepack	72162-2643	72162-2643-03
Nitroglycerin	Nitroglycerin 4 mg/g	OintmentRectal	Solaris Pharma Corporation	73473-500	73473-0500-30
Nitroglycerin	Nitroglycerin .3 mg/1	TabletSublingual	Solco Healthcare U.S., LLC	43547-985	43547-0985-0443547-0985-10
Nitroglycerin	Nitroglycerin .4 mg/1	TabletSublingual	Solco Healthcare U.S., LLC	43547-986	43547-0986-0443547-0986-10
Nitroglycerin	Nitroglycerin .6 mg/1	TabletSublingual	Solco Healthcare U.S., LLC	43547-987	43547-0987-0443547-0987-10
nitroglycerin	Nitroglycerin .4 mg/1	TabletSublingual	REMEDYREPACK INC.	70518-4277	70518-4277-0070518-4277-01
Nitroglycerin	Nitroglycerin 4 mg/g	OintmentRectal	Encube Ethicals, Inc.	21922-048	21922-0048-05
Nitroglycerin	Nitroglycerin 400 ug/1	SprayOral	HF Acquisition Co LLC, DBA HealthFirst	51662-1672	51662-1672-01
Nitroglycerin	Nitroglycerin 4 mg/g	OintmentRectal	Trupharma, LLC	52817-835	52817-0835-30

All 70 Nitroglycerin NDCs