What is NDC 21922-065?

21922-065 is the product NDC for Hydrocortisone, Hydrocortisone 25 mg/g cream, listed with the FDA by Encube Ethicals, Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.

Encube Ethicals, Inc., NDC labeler code 21922. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Hydrocortisone?

169 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Hydrocortisone NDC 21922-065 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)21922-065Labeler and product segments. Claims need a package NDC.

Product NDC at billing width21922-0065Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
21922-065-05	21922006505	1 TUBE in 1 CARTON (21922-065-05) / 30 g in 1 TUBEMarketed from Jun 27, 2026
21922-065-30	21922006530	453.6 g in 1 JAR (21922-065-30)Marketed from Jun 27, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Hydrocortisone
Generic name (nonproprietary): hydrocortisone
Active ingredients: Hydrocortisone — 25 mg/g
Dosage form: Cream
Route: Topical
Labeler: Encube Ethicals, Inc.NDC labeler code 21922
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 203810
Marketing start: Jun 27, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Corticosteroid Hormone Receptor Agonists (Mechanism)
Identifiers: Product ID 21922-065_54e97533-1b55-4a7a-b888-8f6b192ab357SPL ID 54e97533-1b55-4a7a-b888-8f6b192ab357SPL set ID 11e120e2-a1ca-477c-b474-bcbb72656705RxCUI 310891UNII WI4X0X7BPJ
Pharmacologic class: Corticosteroid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N421922006505 followed by a unit qualifier and the quantity

Package 21922-0065-05. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jun 26, 2026.

Indications (excerpt from the label)

INDICATIONS & USAGE SECTION Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroidresponsive dermatoses.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 21922-065

What is NDC 21922-065?: 21922-065 is the product NDC for Hydrocortisone, Hydrocortisone 25 mg/g cream, listed with the FDA by Encube Ethicals, Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Hydrocortisone.
What is the active ingredient?: Hydrocortisone.
Who is the labeler?: Encube Ethicals, Inc., NDC labeler code 21922. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Hydrocortisone?: 169 other product NDCs are listed under this name. See all Hydrocortisone NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Hydrocortisone NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Hydrocortisone	Hydrocortisone 1 g/100g	LotionTopical	Amazon.com Services LLC	72288-469	72288-0469-25
Hydrocortisone	Hydrocortisone 5 mg/1	TabletOral	Solco Healthcare LLC	43547-892	43547-0892-05
Hydrocortisone	Hydrocortisone 10 mg/1	TabletOral	Solco Healthcare LLC	43547-893	43547-0893-10
Hydrocortisone	Hydrocortisone 20 mg/1	TabletOral	Solco Healthcare LLC	43547-894	43547-0894-10
Hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Amazon.com Services LLC	72288-713	72288-0713-64
Hydrocortisone	Hydrocortisone 20 mg/g	GelTopical	Redmont Pharmaceuticals, LLC	71741-455	71741-0455-31
Hydrocortisone	Hydrocortisone 10 mg/g	CreamTopical	Sportpharm LLC	85766-166	85766-0166-1085766-0166-25
hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Sportpharm LLC	85766-151	85766-0151-28
Hydrocortisonehydrocortisone cream 1%	Hydrocortisone 1 g/100g	CreamTopical	Aldermed Inc.	87236-004	87236-0004-09
Hydrocortisonehydrocortisone 1%	Hydrocortisone 1 mg/100g	CreamTopical	PHARMACY CHOICE INC	87228-2010	87228-2010-0187228-2010-05

All 170 Hydrocortisone NDCs