What is NDC 25000-042?

25000-042 is the product NDC for Guaifenesin 600 mg, Guaifenesin 600 mg/1 tablet, listed with the FDA by MARKSANS PHARMA LIMITED. It has 4 package NDCs, shown above in 10- and 11-digit form.

MARKSANS PHARMA LIMITED, NDC labeler code 25000. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Guaifenesin 600 mg?

4 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Guaifenesin 600 mg NDC 25000-042 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)25000-042Labeler and product segments. Claims need a package NDC.

Product NDC at billing width25000-0042Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
25000-042-01	2500000420125000004201	1 BOTTLE in 1 CARTON (25000-042-01) / 20 TABLET in 1 BOTTLEMarketed from Aug 23, 2023
25000-042-12	2500000421225000004212	500 TABLET in 1 BOTTLE (25000-042-12)Marketed from Aug 23, 2023
25000-042-55	2500000425525000004255	2 BLISTER PACK in 1 CARTON (25000-042-55) / 10 TABLET in 1 BLISTER PACKMarketed from Aug 23, 2023
25000-042-99	2500000429925000004299	2 BLISTER PACK in 1 CARTON (25000-042-99) / 20 TABLET in 1 BLISTER PACKMarketed from Apr 18, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Guaifenesin 600 mg
Generic name (nonproprietary): guaifenesin 600 mg
Active ingredients: Guaifenesin — 600 mg/1
Dosage form: Tablet
Route: Oral
Labeler: MARKSANS PHARMA LIMITEDNDC labeler code 25000
Product type: Over-the-counter drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 217780
Marketing start: Aug 23, 2023
Listing expires: Dec 31, 2026
Other FDA classes: Decreased Respiratory Secretion Viscosity (Physiologic effect)Increased Respiratory Secretions (Physiologic effect)
Identifiers: Product ID 25000-042_0af3bdb4-c1f3-4941-a1de-6e08c49849cbSPL ID 0af3bdb4-c1f3-4941-a1de-6e08c49849cbSPL set ID fedf43d0-d6d1-4f50-bbab-396701e45cb2RxCUI 310621, 636522UNII 495W7451VQUPC 0325000042127, 0325000041120, 0325000042554, 0325000041342, 0325000041755, 0325000042011, 0325000042998
Pharmacologic class: Expectorant

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N425000004201 followed by a unit qualifier and the quantity

Package 25000-0042-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Oct 17, 2025.

Indications (excerpt from the label)

INDICATIONS & USAGE SECTION Uses • helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 25000-042

What is NDC 25000-042?: 25000-042 is the product NDC for Guaifenesin 600 mg, Guaifenesin 600 mg/1 tablet, listed with the FDA by MARKSANS PHARMA LIMITED. It has 4 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Guaifenesin 600 mg.
What is the active ingredient?: Guaifenesin.
Who is the labeler?: MARKSANS PHARMA LIMITED, NDC labeler code 25000. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Guaifenesin 600 mg?: 4 other product NDCs are listed under this name. See all Guaifenesin 600 mg NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Guaifenesin 600 mg NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Guaifenesin 600 mgguaifenesin	Guaifenesin 600 mg/1	Tablet, Extended releaseOral	Dr. Reddy's Laboratories Inc.	43598-110	43598-0110-01
Guaifenesin 600 mgguaifenesin	Guaifenesin 600 mg/1	Tablet, Extended releaseOral	CVS Pharmacy	51316-008	51316-0008-01
Guaifenesin 600 mgguaifenesin	Guaifenesin 600 mg/1	Tablet, Extended releaseOral	Dr. Reddy's Laboratories Inc.	43598-008	43598-0008-0143598-0008-40
Guaifenesin 600 mgguaifenesin	Guaifenesin 600 mg/1	Tablet, Extended releaseOral	Strategic Sourcing Services, LLC	70677-1257	70677-1257-0170677-1257-02

Other NDCs under ANDA 217780

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 217780
Product	Strength	Form · route	Labeler	Product NDC
Mucus Reliefguaifenesin	Guaifenesin 1200 mg/1	Tablet, Extended releaseOral	BJWC (Berkley & Jensen / BJ's)	68391-724
Maximum Strength Mucus Reliefguaifenesin	Guaifenesin 1200 mg/1	Tablet, Extended releaseOral	SAM'S WEST INC	68196-033
Mucus Reliefguaifenesin	Guaifenesin 600 mg/1	Tablet, Extended releaseOral	Grocery Outlet, Inc.	85828-723
Mucus Relief ERguaifenesin	Guaifenesin 1200 mg/1	Tablet, Extended releaseOral	Rugby Laboratories	0536-1249
Mucus Reliefguaifenesin	Guaifenesin 1200 mg/1	Tablet, Extended releaseOral	CVS Pharmacy	51316-724
Mucus Reliefguaifenesin	Guaifenesin 600 mg/1	Tablet, Extended releaseOral	KROGER COMPANY	41226-723
Maximum Strength Mucus Reliefguaifenesin	Guaifenesin 1200 mg/1	Tablet, Extended releaseOral	KROGER COMPANY	41226-724
Mucus Reliefguaifenesin	Guaifenesin 1200 mg/1	Tablet, Extended releaseOral	LEADER/ Cardinal Health 110, Inc.	70000-0730
Guaifenesin Extended Release 600 mgguaifenesin	Guaifenesin 600 mg/1	TabletOral	TIME CAP LABORATORIES, INC.	49483-723
Guaifenesin Extended Release 1200 mgguaifenesin	Guaifenesin 1200 mg/1	TabletOral	TIME CAP LABORATORIES, INC.	49483-724
Guaifenesin 1200 mg	Guaifenesin 1200 mg/1	TabletOral	MARKSANS PHARMA LIMITED	25000-041