NDC codes

FDA NDC Directory
Product NDC (as listed)25021-319Labeler and product segments. Claims need a package NDC.
Product NDC at billing width25021-0319Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
25021-319-052502103190510 VIAL in 1 CARTON (25021-319-05) / 5 mL in 1 VIALMarketed from Jun 1, 2024
25021-319-102502103191010 VIAL in 1 CARTON (25021-319-10) / 10 mL in 1 VIALMarketed from Jun 1, 2024
25021-319-252502103192510 VIAL in 1 CARTON (25021-319-25) / 25 mL in 1 VIALMarketed from Jun 1, 2024

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Diltiazem Hydrochloride
Generic name (nonproprietary)
diltiazem hydrochloride
Active ingredients
Diltiazem hydrochloride — 5 mg/mL
Dosage form
Injection, Solution
Route
Intravenous
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 074617
Marketing start
Listing expires
Other FDA classes
Calcium Channel Antagonists (Mechanism)Cytochrome P450 3A4 Inhibitors (Mechanism)
Identifiers
Product ID 25021-319_2b627626-b2f9-48d1-90d1-f51acbbc8e20SPL ID 2b627626-b2f9-48d1-90d1-f51acbbc8e20SPL set ID 9d51c0f6-26b7-4220-83fb-4e736b289e64RxCUI 1791229, 1791232, 1791233UNII OLH94387TE
Pharmacologic class
Calcium Channel Blocker

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N425021031905 followed by a unit qualifier and the quantity

Package 25021-0319-05. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

INDICATIONS AND USAGE Diltiazem hydrochloride injection is indicated for the following: Atrial Fibrillation or Atrial Flutter Temporary control of rapid ventricular rate in atrial fibrillation or atrial flutter. It should not be used in patients with atrial fibrillation or atrial flutter associated with an accessory bypass tract such as in Wolff-Parkinson-White (WPW) syndrome or short PR syndrome. Paroxysmal Supraventricular Tachycardia Rapid conversion of paroxysmal supraventricular tachycardias (PSVT) to sinus rhythm. This includes AV nodal reentrant tachycardias and reciprocating tachycardias associated with an extranodal accessory pathway such as the WPW syndrome or short PR syndrome. Un…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 074617

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 074617
ProductStrengthForm · routeLabelerProduct NDC
Diltiazem HydrochlorideDiltiazem hydrochloride 5 mg/mLInjection, SolutionIntravenousHF Acquisition Co. LLC DBA HealthFirst51662-1712
Diltiazem HydrochlorideDiltiazem hydrochloride 5 mg/mLInjection, SolutionIntravenousProPharma Distribution84549-319
Diltiazem HydrochlorideDiltiazem hydrochloride 5 mg/mLInjection, SolutionIntravenousMedical Purchasing Solutions, LLC71872-7345

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