What is NDC 25021-601?

25021-601 is the product NDC for caffeine citrate, Caffeine citrate 20 mg/mL solution, listed with the FDA by Sagent Pharmaceuticals. It has 1 package NDC, shown above in 10- and 11-digit form.

Sagent Pharmaceuticals, NDC labeler code 25021. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for caffeine citrate?

12 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

caffeine citrate NDC 25021-601 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)25021-601Labeler and product segments. Claims need a package NDC.

Product NDC at billing width25021-0601Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
25021-601-03	2502106010325021060103	1 VIAL in 1 CARTON (25021-601-03) / 3 mL in 1 VIALMarketed from Sep 15, 2012

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): caffeine citrate
Generic name (nonproprietary): caffeine citrate
Active ingredients: Caffeine citrate — 20 mg/mL
Dosage form: Solution
Route: Intravenous
Labeler: Sagent PharmaceuticalsNDC labeler code 25021
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 090827
Marketing start: Sep 15, 2012
Listing expires: Dec 31, 2027
Other FDA classes: Central Nervous System Stimulation (Physiologic effect)Xanthines (Chemical structure)
Identifiers: Product ID 25021-601_73d572f6-4f18-4198-9ffa-ec68ce101711SPL ID 73d572f6-4f18-4198-9ffa-ec68ce101711SPL set ID 5f38c395-0093-4afd-89ec-f96e5dc0934aRxCUI 849928, 849931UNII U26EO4675Q
Pharmacologic class: Central Nervous System Stimulant; Methylxanthine

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N425021060103 followed by a unit qualifier and the quantity

Package 25021-0601-03. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jul 29, 2026.

Indications (excerpt from the label)

INDICATIONS AND USAGE Caffeine citrate is indicated for the treatment of apnea of prematurity.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 25021-601

What is NDC 25021-601?: 25021-601 is the product NDC for caffeine citrate, Caffeine citrate 20 mg/mL solution, listed with the FDA by Sagent Pharmaceuticals. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: caffeine citrate.
What is the active ingredient?: Caffeine citrate.
Who is the labeler?: Sagent Pharmaceuticals, NDC labeler code 25021. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for caffeine citrate?: 12 other product NDCs are listed under this name. See all caffeine citrate NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other caffeine citrate NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Caffeine Citrate	Caffeine citrate 20 mg/mL	InjectionIntravenous	Hikma Pharmaceuticals USA Inc.	0641-6267	00641-6267-10
Caffeine Citrate	Caffeine citrate 20 mg/mL	SolutionOral	Sun Pharmaceutical Industries, Inc.	47335-290	47335-0290-44
Caffeine Citrate	Caffeine citrate 60 mg/3mL	SolutionOral	Micro Labs Limited	42571-346	42571-0346-6942571-0346-96
Caffeine Citrate	Caffeine citrate 60 mg/3mL	InjectionIntravenous	Armas Pharmaceuticals Inc.	72485-104	72485-0104-0172485-0104-10
Caffeine Citrate	Caffeine citrate 60 mg/3mL	Injection, SolutionIntramuscular, Intravenous	Micro Labs Limited	42571-244	42571-0244-98
Caffeine Citrate	Caffeine citrate 20 mg/mL	Injection, SolutionIntravenous	Eugia US LLC	55150-187	55150-0187-03
caffeine citrate	Caffeine citrate 20 mg/mL	InjectionIntravenous	Exela Pharma Sciences, LLC	51754-0500	51754-0500-01
Caffeine Citrate	Caffeine citrate 20 mg/mL	InjectionIntravenous	Sun Pharmaceutical Industries, Inc.	47335-289	47335-0289-27
caffeine citrate	Caffeine citrate 20 mg/mL	SolutionOral	Sagent Pharmaceuticals	25021-602	25021-0602-03
Caffeine Citrate	Caffeine citrate 20 mg/mL	SolutionOral	Fresenius Kabi USA, LLC	63323-406	63323-0406-03

All 13 caffeine citrate NDCs