What is NDC 25021-652?

25021-652 is the product NDC for ropivacaine hydrochloride, Ropivacaine hydrochloride 5 mg/mL injection, solution, listed with the FDA by Sagent Pharmaceuticals. It has 2 package NDCs, shown above in 10- and 11-digit form.

Sagent Pharmaceuticals, NDC labeler code 25021. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for ropivacaine hydrochloride?

65 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

ropivacaine hydrochloride NDC 25021-652

NDC codes

FDA NDC Directory

Product NDC (as listed)25021-652Labeler and product segments. Claims need a package NDC.

Product NDC at billing width25021-0652Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
25021-652-82	2502106528225021065282	10 BAG in 1 CARTON (25021-652-82) / 100 mL in 1 BAGMarketed from Jul 15, 2019
25021-652-87	2502106528725021065287	10 BAG in 1 CARTON (25021-652-87) / 200 mL in 1 BAGMarketed from Jul 15, 2019

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): ropivacaine hydrochloride
Generic name (nonproprietary): ropivacaine hydrochloride
Active ingredients: Ropivacaine hydrochloride — 5 mg/mL
Dosage form: Injection, Solution
Route: Epidural, Infiltration
Labeler: Sagent PharmaceuticalsNDC labeler code 25021
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 206166
Marketing start: Jul 15, 2019
Listing expires: Dec 31, 2027
Other FDA classes: Amides (Chemical structure)Local Anesthesia (Physiologic effect)
Identifiers: Product ID 25021-652_41f4446a-ca6e-465e-9a79-8c4f99eb1ac3SPL ID 41f4446a-ca6e-465e-9a79-8c4f99eb1ac3SPL set ID 8c5c762f-d266-4b1a-809e-f11bfc89bc2dRxCUI 1734347, 1734355, 1734479, 1734481UNII V910P86109
Pharmacologic class: Amide Local Anesthetic

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

NDC on a medical claim

N425021065282 followed by a unit qualifier and the quantity

Package 25021-0652-82. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Aug 6, 2025.

Indications (excerpt from the label)

Ropivacaine Hydrochloride Injection is indicated for the production of local or regional anesthesia for surgery and for acute pain management. Surgical Anesthesia : epidural block for surgery including cesarean section; major nerve block; local infiltration Acute Pain Management : epidural continuous infusion or intermittent bolus, e.g., postoperative or labor; local infiltration Ropivacaine Hydrochloride Injection is an amide local anesthetic indicated in adults for the production of local or regional anesthesia for surgery and for acute pain management ( 1 ). Surgical Anesthesia : epidural block for surgery including cesarean section; major nerve block; local infiltration ( 1 ) Acute Pain …

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 25021-652

What is NDC 25021-652?: 25021-652 is the product NDC for ropivacaine hydrochloride, Ropivacaine hydrochloride 5 mg/mL injection, solution, listed with the FDA by Sagent Pharmaceuticals. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: ropivacaine hydrochloride.
What is the active ingredient?: Ropivacaine hydrochloride.
Who is the labeler?: Sagent Pharmaceuticals, NDC labeler code 25021. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for ropivacaine hydrochloride?: 65 other product NDCs are listed under this name. See all ropivacaine hydrochloride NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other ropivacaine hydrochloride NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Ropivacaine Hydrochloride	Ropivacaine hydrochloride 150 mg/30mL	InjectionEpidural, Infiltration, Perineural	Armas Pharmaceuticals Inc.	72485-519	72485-0519-10
Ropivacaine Hydrochloride	Ropivacaine hydrochloride 2 mg/mL	InjectionEpidural, Infiltration	Hikma Pharmaceuticals USA Inc.	0143-9263	00143-9263-10
Ropivacaine Hydrochloride	Ropivacaine hydrochloride 5 mg/mL	InjectionEpidural, Infiltration	Hikma Pharmaceuticals USA Inc.	0143-9264	00143-9264-10
Ropivacaine Hydrochloride	Ropivacaine hydrochloride 7.5 mg/mL	InjectionEpidural	Hikma Pharmaceuticals USA Inc.	0143-9265	00143-9265-10
Ropivacaine Hydrochloride	Ropivacaine hydrochloride 10 mg/mL	InjectionEpidural	Hikma Pharmaceuticals USA Inc.	0143-9266	00143-9266-10
Ropivacaine Hydrochloride	Ropivacaine hydrochloride 2 mg/mL	Injection, SolutionEpidural, Infiltration, Perineural	Hikma Pharmaceuticals USA Inc.	0143-9195	00143-9195-24
Ropivacaine Hydrochloride	Ropivacaine hydrochloride 2 mg/mL	Injection, SolutionEpidural, Infiltration, Perineural	Hikma Pharmaceuticals USA Inc.	0143-9196	00143-9196-12
Ropivacaine Hydrochloride	Ropivacaine hydrochloride 5 mg/mL	Injection, SolutionEpidural, Infiltration, Perineural	Hikma Pharmaceuticals USA Inc.	0143-9197	00143-9197-24
Ropivacaine Hydrochloride	Ropivacaine hydrochloride 2 mg/mL	Injection, SolutionEpidural, Infiltration	Glenmark Pharmaceuticals Inc., USA	68462-777	68462-0777-35
Ropivacaine Hydrochloride	Ropivacaine hydrochloride 5 mg/mL	Injection, SolutionEpidural, Infiltration, Perineural	Glenmark Pharmaceuticals Inc., USA	68462-778	68462-0778-5568462-0778-74

All 66 ropivacaine hydrochloride NDCs

Other NDCs under ANDA 206166

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 206166
Product	Strength	Form · route	Labeler	Product NDC
ropivacaine hydrochloride	Ropivacaine hydrochloride 2 mg/mL	Injection, SolutionEpidural, Infiltration	Sagent Pharmaceuticals	25021-671