NDC codes

FDA NDC Directory
Product NDC (as listed)39822-5525Labeler and product segments. Claims need a package NDC.
Product NDC at billing width39822-5525Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
39822-5525-33982255250325 AMPULE in 1 CARTON (39822-5525-3) / 1 mL in 1 AMPULE (39822-5525-2)Marketed from Jan 30, 2015

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Promethazine Hydrochloride
Generic name (nonproprietary)
promethazine hydrochloride
Active ingredients
Promethazine hydrochloride — 25 mg/mL
Dosage form
Injection, Solution
Route
Intramuscular, Intravenous
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 040737
Marketing start
Listing expires
Other FDA classes
Phenothiazines (Chemical structure)
Identifiers
Product ID 39822-5525_0e3526e1-38be-1d89-e063-6294a90a775dSPL ID 0e3526e1-38be-1d89-e063-6294a90a775dSPL set ID 1d02d52b-84bb-4e81-b352-125029eb39f6RxCUI 992460UNII R61ZEH7I1I
Pharmacologic class
Phenothiazine

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N439822552503 followed by a unit qualifier and the quantity

Package 39822-5525-03. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS AND USAGE Promethazine hydrochloride injection is indicated for the following conditions: Amelioration of allergic reactions to blood or plasma. In anaphylaxis as an adjunct to epinephrine and other standard measures after the acute symptoms have been controlled. For other uncomplicated allergic conditions of the immediate type when oral therapy is impossible or contraindicated. For sedation and relief of apprehension and to produce light sleep from which the patient can be easily aroused. Active treatment of motion sickness. Prevention and control of nausea and vomiting associated with certain types of anesthesia and surgery. As an adjunct to analgesics for the control of postop…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 040737

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 040737
ProductStrengthForm · routeLabelerProduct NDC
Promethazine HydrochloridePromethazine hydrochloride 25 mg/mLInjection, SolutionIntramuscular, IntravenousProPharma Distribution84549-525
Promethazine HydrochloridePromethazine hydrochloride 50 mg/mLInjection, SolutionIntramuscular, IntravenousXGen Pharmaceuticals DJB, Inc.39822-5550

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