What is NDC 42291-898?

42291-898 is the product NDC for Venlafaxine Hydrochloride, Venlafaxine hydrochloride 75 mg/1 capsule, extended release, listed with the FDA by AvKARE. It has 3 package NDCs, shown above in 10- and 11-digit form.

AvKARE, NDC labeler code 42291. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Venlafaxine Hydrochloride?

207 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Venlafaxine Hydrochloride NDC 42291-898

NDC codes

FDA NDC Directory

Product NDC (as listed)42291-898Labeler and product segments. Claims need a package NDC.

Product NDC at billing width42291-0898Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
42291-898-30	4229108983042291089830	30 CAPSULE, EXTENDED RELEASE in 1 BOTTLE (42291-898-30)Marketed from Jun 21, 2021
42291-898-50	4229108985042291089850	500 CAPSULE, EXTENDED RELEASE in 1 BOTTLE (42291-898-50)Marketed from Jun 21, 2021
42291-898-90	4229108989042291089890	90 CAPSULE, EXTENDED RELEASE in 1 BOTTLE (42291-898-90)Marketed from Jul 10, 2013

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Venlafaxine Hydrochloride
Generic name (nonproprietary): venlafaxine hydrochloride
Active ingredients: Venlafaxine hydrochloride — 75 mg/1
Dosage form: Capsule, Extended release
Route: Oral
Labeler: AvKARENDC labeler code 42291
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 076565
Marketing start: Jul 10, 2013
Listing expires: Dec 31, 2027
Other FDA classes: Norepinephrine Uptake Inhibitors (Mechanism)Serotonin Uptake Inhibitors (Mechanism)
Identifiers: Product ID 42291-898_488438c1-31da-f4c3-e063-6394a90a9a38SPL ID 488438c1-31da-f4c3-e063-6394a90a9a38SPL set ID 7f224c88-9425-9ef0-01bc-dcf3bdafbd89RxCUI 313581, 313583, 313585UNII 7D7RX5A8MO
Pharmacologic class: Serotonin and Norepinephrine Reuptake Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N442291089830 followed by a unit qualifier and the quantity

Package 42291-0898-30. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jan 16, 2026. This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS AND USAGE 1.1 Major Depressive Disorder Venlafaxine hydrochloride extended-release capsules are indicated for the treatment of major depressive disorder (MDD). Efficacy was established in three short-term (4, 8, and 12 weeks) and two long-term, maintenance trials. 1.2 Generalized Anxiety Disorder Venlafaxine hydrochloride extended-release capsules are indicated for the treatment of Generalized Anxiety Disorder (GAD). Efficacy was established in two 8-week and two 26-week placebo-controlled trials. 1.3 Social Anxiety Disorder Venlafaxine hydrochloride extended-release capsules are indicated for the treatment of Social Anxiety Disorder (SAD), also known as social phobia. Efficacy w…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 42291-898

What is NDC 42291-898?: 42291-898 is the product NDC for Venlafaxine Hydrochloride, Venlafaxine hydrochloride 75 mg/1 capsule, extended release, listed with the FDA by AvKARE. It has 3 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Venlafaxine Hydrochloride.
What is the active ingredient?: Venlafaxine hydrochloride.
Who is the labeler?: AvKARE, NDC labeler code 42291. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Venlafaxine Hydrochloride?: 207 other product NDCs are listed under this name. See all Venlafaxine Hydrochloride NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Venlafaxine Hydrochloride NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 37.5 mg/1	Capsule, Extended releaseOral	PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS	24658-125	24658-0125-1024658-0125-3024658-0125-90
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 75 mg/1	Capsule, Extended releaseOral	PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS	24658-126	24658-0126-1024658-0126-3024658-0126-90
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 150 mg/1	Capsule, Extended releaseOral	PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS	24658-127	24658-0127-0524658-0127-3024658-0127-90
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 75 mg/1	Capsule, Extended releaseOral	Coupler LLC	67046-0390	67046-0390-03
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 37.5 mg/1	Capsule, Extended releaseOral	Coupler LLC	67046-0527	67046-0527-03
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 37.5 mg/1	Capsule, Extended releaseOral	NorthStar RxLLC	72603-747	72603-0747-01
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 75 mg/1	Capsule, Extended releaseOral	NorthStar RxLLC	72603-748	72603-0748-01
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 150 mg/1	Capsule, Extended releaseOral	NorthStar RxLLC	72603-749	72603-0749-01
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 75 mg/1	Capsule, Extended releaseOral	REMEDYREPACK INC.	70518-4632	70518-4632-00
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 37.5 mg/1	Capsule, Extended releaseOral	Advanced Rx of Tennessee, LLC	80425-0581	80425-0581-0180425-0581-0280425-0581-03

All 208 Venlafaxine Hydrochloride NDCs

Other NDCs under ANDA 076565

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 076565
Product	Strength	Form · route	Labeler	Product NDC
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 75 mg/1	Capsule, Extended releaseOral	Proficient Rx LP	63187-177
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 75 mg/1	Capsule, Extended releaseOral	QPharma, Inc.	42708-054
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 37.5 mg/1	Capsule, Extended releaseOral	AvKARE	42291-897
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 150 mg/1	Capsule, Extended releaseOral	AvKARE	42291-899
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 150 mg/1	Capsule, Extended releaseOral	Proficient Rx LP	63187-420
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 37.5 mg/1	Capsule, Extended releaseOral	Teva Pharmaceuticals USA, Inc.	0093-7384
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 75 mg/1	Capsule, Extended releaseOral	Teva Pharmaceuticals USA, Inc.	0093-7385
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 75 mg/1	Capsule, Extended releaseOral	A-S Medication Solutions	50090-6214
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 150 mg/1	Capsule, Extended releaseOral	Teva Pharmaceuticals USA, Inc.	0093-7386
Venlafaxine Hydrochloride	Venlafaxine hydrochloride 37.5 mg/1	Capsule, Extended releaseOral	Proficient Rx LP	63187-481