NDC codes

FDA NDC Directory
Product NDC (as listed)42385-907Labeler and product segments. Claims need a package NDC.
Product NDC at billing width42385-0907Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
42385-907-15423850907151 BLISTER PACK in 1 CARTON (42385-907-15) / 15 TABLET, FILM COATED in 1 BLISTER PACKMarketed from May 15, 2026
42385-907-304238509073030 TABLET, FILM COATED in 1 BOTTLE (42385-907-30)Marketed from May 15, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Macitentan
Generic name (nonproprietary)
macitentan
Active ingredients
Macitentan — 10 mg/1
Dosage form
Tablet, Film coated
Route
Oral
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 211120
Marketing start
Listing expires
Other FDA classes
Endothelin Receptor Antagonists (Mechanism)
Identifiers
Product ID 42385-907_93f0ab4a-4756-4915-a000-ed65b26cd61cSPL ID 93f0ab4a-4756-4915-a000-ed65b26cd61cSPL set ID 93f0ab4a-4756-4915-a000-ed65b26cd61cRxCUI 1442137UNII Z9K9Y9WMVL
Pharmacologic class
Endothelin Receptor Antagonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N442385090715 followed by a unit qualifier and the quantity

Package 42385-0907-15. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

Macitentan tablets are an endothelin receptor antagonist (ERA) indicated for the treatment of pulmonary arterial hypertension (PAH, WHO Group I) in adults to reduce the risks of disease progression and hospitalization for PAH ( 1.1 ). 1.1 Pulmonary Arterial Hypertension Macitentan tablets are an endothelin receptor antagonist (ERA) indicated for the treatment of pulmonary arterial hypertension (PAH, WHO Group I) in adults to reduce the risks of disease progression and hospitalization for PAH. Effectiveness was established in a long-term study in PAH patients with predominantly WHO Functional Class II to III symptoms treated for an average of 2 years. Patients had idiopathic and heritable PAH…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

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