What is NDC 42681-0058?

42681-0058 is the product NDC for 365 Whole Foods Market Fluticasone Propionate, Fluticasone propionate 50 ug/1 spray, metered, listed with the FDA by Whole Foods Market, Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

365 Whole Foods Market Fluticasone Propionate (Fluticasone propionate).

Whole Foods Market, Inc., NDC labeler code 42681. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for 365 Whole Foods Market Fluticasone Propionate?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

NDC 42681-0058

NDC codes

FDA NDC Directory

Product NDC (as listed)42681-0058Labeler and product segments. Claims need a package NDC.

Product NDC at billing width42681-0058Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
42681-0058-1	4268100580142681005801	1 BOTTLE in 1 CARTON (42681-0058-1) / 60 SPRAY, METERED in 1 BOTTLEMarketed from Jan 22, 2026

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): 365 Whole Foods Market Fluticasone Propionate
Generic name (nonproprietary): fluticasone propionate
Active ingredients: Fluticasone propionate — 50 ug/1
Dosage form: Spray, Metered
Route: Nasal
Labeler: Whole Foods Market, Inc.NDC labeler code 42681
Product type: Over-the-counter drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 217088
Marketing start: Jan 22, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Corticosteroid Hormone Receptor Agonists (Mechanism)
Identifiers: Product ID 42681-0058_313517bd-cb08-49a5-8ef1-e5522cc21c80SPL ID 313517bd-cb08-49a5-8ef1-e5522cc21c80SPL set ID 313517bd-cb08-49a5-8ef1-e5522cc21c80RxCUI 1797907UNII O2GMZ0LF5W
Pharmacologic class: Corticosteroid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Nasal products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N442681005801 followed by a unit qualifier and the quantity

Package 42681-0058-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jan 22, 2026.

Indications (excerpt from the label)

Uses Temporarily relieves these symptoms of hay fever or other upper respiratory allergies: nasal congestion itchy, watery eyes itchy nose runny nose sneezing

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 42681-0058

What is NDC 42681-0058?: 42681-0058 is the product NDC for 365 Whole Foods Market Fluticasone Propionate, Fluticasone propionate 50 ug/1 spray, metered, listed with the FDA by Whole Foods Market, Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: 365 Whole Foods Market Fluticasone Propionate (Fluticasone propionate).
What is the active ingredient?: Fluticasone propionate.
Who is the labeler?: Whole Foods Market, Inc., NDC labeler code 42681. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for 365 Whole Foods Market Fluticasone Propionate?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other NDCs under ANDA 217088

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 217088
Product	Strength	Form · route	Labeler	Product NDC
Childrens Fluticasone Propionatefluticasone propionate	Fluticasone propionate 50 ug/1	Spray, MeteredNasal	Aurohealth LLC	58602-018
Fluticarefluticasone propionate	Fluticasone propionate 50 ug/1	Spray, MeteredNasal	INNOVUS PHARMACEUTICALS, INC.	57483-180
Fluticasone Propionate	Fluticasone propionate 50 ug/1	Spray, MeteredNasal	Family Dollar Stores, LLC	55319-058
Fluticasone Propionate	Fluticasone propionate 50 ug/1	Spray, MeteredNasal	Aurohealth LLC	58602-017
Fluticasone Propionate	Fluticasone propionate 50 ug/1	Spray, MeteredNasal	YYBA Corp	73581-510
Mucinex Nasal Congestion and Allergy Relieffluticasone propionate	Fluticasone propionate 50 ug/1	Spray, MeteredNasal	Reckitt Benckiser LLC	72854-227

365 Whole Foods Market Fluticasone Propionate (Fluticasone propionate) NDC 42681-0058