MS Contin (morphine sulfate) NDC 42858-631

NDC codes

FDA NDC Directory

Product NDC (as listed)42858-631Labeler and product segments. Claims need a package NDC.

Product NDC at billing width42858-0631Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
42858-631-01	42858063101	100 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (42858-631-01)Marketed from May 15, 2017

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): MS Contin
Generic name (nonproprietary): morphine sulfate
Active ingredients: Morphine sulfate — 30 mg/1
Dosage form: Tablet, Film coated, Extended release
Route: Oral
Labeler: Rhodes Pharmaceuticals LLC
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 019516
Marketing start: May 15, 2017
Listing expires: Dec 31, 2027
DEA schedule: CII
Other FDA classes: Full Opioid Agonists (Mechanism)
Identifiers: Product ID 42858-631_8a5edf84-32d5-44f2-afad-7589689f3175SPL ID 8a5edf84-32d5-44f2-afad-7589689f3175SPL set ID c354b3bf-86c0-4bb8-8b1f-be2164942698RxCUI 891881, 891888, 891893, 892574, 892660, 894813UNII X3P646A2J0UPC 0342858631013, 0342858515016, 0342858760010
Pharmacologic class: Opioid Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N442858063101 followed by a unit qualifier and the quantity

Package 42858-0631-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Aug 14, 2026. This label includes a boxed warning.

Indications (excerpt from the label)

MS CONTIN is indicated for the management of severe and persistent pain that requires an opioid analgesic and that cannot be adequately treated with alternative options, including immediate-release opioids. Limitations of Use Because of the risks of addiction, abuse, misuse, overdose, and death, which can occur at any dosage or duration and persist over the course of therapy [see Warnings and Precautions (5.2) ] , reserve opioid analgesics, including MS CONTIN, for use in patients for whom alternative treatment options are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain. MS CONTIN is not indicated as an as-needed (prn) analgesic. MS CONTI…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 019516

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 019516
Product	Strength	Form · route	Labeler	Product NDC
MS Continmorphine sulfate	Morphine sulfate 15 mg/1	Tablet, Film coated, Extended releaseOral	Rhodes Pharmaceuticals LLC	42858-515
MS Continmorphine sulfate	Morphine sulfate 60 mg/1	Tablet, Film coated, Extended releaseOral	Rhodes Pharmaceuticals LLC	42858-760