What is NDC 46122-818?

46122-818 is the product NDC for Acetaminophen and Ibuprofen, Ibuprofen 125 mg/1; Acetaminophen 250 mg/1 tablet, film coated, listed with the FDA by AMERISOURCE BERGEN. It has 1 package NDC, shown above in 10- and 11-digit form.

AMERISOURCE BERGEN, NDC labeler code 46122. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Acetaminophen and Ibuprofen?

18 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Acetaminophen and Ibuprofen NDC 46122-818

NDC codes

FDA NDC Directory

Product NDC (as listed)46122-818Labeler and product segments. Claims need a package NDC.

Product NDC at billing width46122-0818Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
46122-818-61	46122081861	1 BOTTLE in 1 CARTON (46122-818-61) / 80 TABLET, FILM COATED in 1 BOTTLEMarketed from May 15, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Acetaminophen and Ibuprofen
Generic name (nonproprietary): acetaminophen and ibuprofen
Active ingredients: Ibuprofen — 125 mg/1Acetaminophen — 250 mg/1
Dosage form: Tablet, Film coated
Route: Oral
Labeler: AMERISOURCE BERGENNDC labeler code 46122
Product type: Over-the-counter drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 216999
Marketing start: May 15, 2025
Listing expires: Dec 31, 2026
Other FDA classes: Non-Steroidal (Chemical structure)Cyclooxygenase Inhibitors (Mechanism)
Identifiers: Product ID 46122-818_35313676-9f45-76fc-e063-6294a90a24a9SPL ID 35313676-9f45-76fc-e063-6294a90a24a9SPL set ID 353136b4-884d-baa2-e063-6394a90a89e9RxCUI 2387532UNII WK2XYI10QM, 362O9ITL9D
Pharmacologic class: Nonsteroidal Anti-inflammatory Drug

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N446122081861 followed by a unit qualifier and the quantity

Package 46122-0818-61. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective May 15, 2025.

Indications (excerpt from the label)

Uses temporarily relieves minor aches and pains due to: ■ headache ■ toothache ■ backache ■ menstrual cramps ■ muscular aches ■ minor pain of arthritis

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 46122-818

What is NDC 46122-818?: 46122-818 is the product NDC for Acetaminophen and Ibuprofen, Ibuprofen 125 mg/1; Acetaminophen 250 mg/1 tablet, film coated, listed with the FDA by AMERISOURCE BERGEN. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Acetaminophen and Ibuprofen.
What is the active ingredient?: Ibuprofen, Acetaminophen.
Who is the labeler?: AMERISOURCE BERGEN, NDC labeler code 46122. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Acetaminophen and Ibuprofen?: 18 other product NDCs are listed under this name. See all Acetaminophen and Ibuprofen NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Acetaminophen and Ibuprofen NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Acetaminophen and Ibuprofenacetaminophen, ibuprofen	Acetaminophen 250 mg/1; Ibuprofen 125 mg/1	Tablet, Film coatedOral	L.N.K. International, Inc.	50844-598	50844-0598-1450844-0598-19
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	CVS Pharmacy	51316-955	51316-0955-1151316-0955-78
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	BIONPHARMA INC.	69452-469	69452-0469-22
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	Meijer Distribution Inc	79481-6501	79481-6501-07
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	WALGREEN COMPANY	0363-4081	00363-4081-78
Acetaminophen and Ibuprofen	Acetaminophen 250 mg/1; Ibuprofen 125 mg/1	Tablet, Film coatedOral	Aurohealth LLC	58602-893	58602-0893-0158602-0893-0258602-0893-03+27 more
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	TabletOral	WAL-MART STORES INC.	79903-244	79903-0244-44
Acetaminophen and Ibuprofen	Acetaminophen 250 mg/1; Ibuprofen 125 mg/1	TabletOral	Family Dollar	55319-139	55319-0139-36
Acetaminophen and Ibuprofen	Acetaminophen 250 mg/1; Ibuprofen 125 mg/1	TabletOral	CVS	51316-132	51316-0132-7251316-0132-81
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	TabletOral	CVS	51316-131	51316-0131-3651316-0131-4451316-0131-72

All 19 Acetaminophen and Ibuprofen NDCs

Other NDCs under ANDA 216999

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 216999
Product	Strength	Form · route	Labeler	Product NDC
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	WALGREEN COMPANY	0363-4081
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	AMERISOURCE BERGEN	46122-742
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	CVS Pharmacy	51316-955
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	DISCOUNT DRUG MART, INC.	53943-034
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	Bionpharma Inc.	69452-394
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	BIONPHARMA INC.	69452-469
Acetaminophen and Ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	Meijer Distribution Inc	79481-6501
dual action pain relieveracetaminophen and ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	Bionpharma Inc.	69452-446
dual action pain relieveracetaminophen and ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	Bionpharma Inc.	69452-447
dual action pain relieveracetaminophen and ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	CHAIN DRUG MARKETING ASSOCIATION INC.	83324-149
dual action pain relieveracetaminophen and ibuprofen	Ibuprofen 125 mg/1; Acetaminophen 250 mg/1	Tablet, Film coatedOral	CHAIN DRUG MARKETING ASSOCIATION INC.	83324-178