What is NDC 49281-726?

49281-726 is the product NDC for Flublok Trivalent Northern Hemisphere, Influenza a virus a/missouri/11/2025 (H1n1) recombinant hemagglutinin antigen 45 ug/.5mL + 2 more ingredients injection, listed with the FDA by Sanofi Vaccines US Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Flublok Trivalent Northern Hemisphere (INFLUENZA A VIRUS A/Missouri/11/2025 (H1N1) RECOMBINANT HEMAGGLUTININ ANTIGEN, INFLUENZA A VIRUS A/Darwin/1415/2025 (H3N2) RECOMBINANT HEMAGGLUTININ ANTIGEN, and INFLUENZA B VIRUS B/Pennsylvania/14/2025 RECOMBINANT HEMAGGLUTININ ANTIGEN).

What is the active ingredient?

Influenza a virus a/missouri/11/2025 (H1n1) recombinant hemagglutinin antigen, Influenza a virus a/darwin/1415/2025 (H3n2) recombinant hemagglutinin antigen, Influenza b virus b/pennsylvania/14/2025 recombinant hemagglutinin antigen.

Sanofi Vaccines US Inc., NDC labeler code 49281. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Flublok Trivalent Northern Hemisphere?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Flublok Trivalent Northern Hemisphere NDC 49281-726

NDC codes

FDA NDC Directory

Product NDC (as listed)49281-726Labeler and product segments. Claims need a package NDC.

Product NDC at billing width49281-0726Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
49281-726-10	4928107261049281072610	10 SYRINGE in 1 CARTON (49281-726-10) / .5 mL in 1 SYRINGE (49281-726-88)Marketed from Jul 2, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Flublok Trivalent Northern Hemisphere
Generic name (nonproprietary): influenza a virus a/missouri/11/2025 (h1n1) recombinant hemagglutinin antigen, influenza a virus a/darwin/1415/2025 (h3n2) recombinant hemagglutinin antigen, and influenza b virus b/pennsylvania/14/2025 recombinant hemagglutinin antigen
Active ingredients: Influenza a virus a/missouri/11/2025 (H1n1) recombinant hemagglutinin antigen — 45 ug/.5mLInfluenza a virus a/darwin/1415/2025 (H3n2) recombinant hemagglutinin antigen — 45 ug/.5mLInfluenza b virus b/pennsylvania/14/2025 recombinant hemagglutinin antigen — 45 ug/.5mL
Dosage form: Injection
Route: Intramuscular
Labeler: Sanofi Vaccines US Inc.NDC labeler code 49281
Product type: Vaccine
Marketing category: BLA — Biologics License ApplicationApplication BLA 125285
Marketing start: Jul 2, 2026
Marketing end: Jun 30, 2027
Identifiers: Product ID 49281-726_92606719-3e37-477b-baf9-453cb34f3f50SPL ID 92606719-3e37-477b-baf9-453cb34f3f50

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Immunization administration (CPT 90460–90474)

Giving a vaccine is reported separately from the vaccine product code, with an immunization administration code. Which code applies depends on the patient's age, the route and whether counselling was provided.

How CPT relates to drug billing

NDC on a medical claim

N449281072610 followed by a unit qualifier and the quantity

Package 49281-0726-10. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

The FDA listing for this product does not reference a label (SPL) set.

About NDC 49281-726

What is NDC 49281-726?: 49281-726 is the product NDC for Flublok Trivalent Northern Hemisphere, Influenza a virus a/missouri/11/2025 (H1n1) recombinant hemagglutinin antigen 45 ug/.5mL + 2 more ingredients injection, listed with the FDA by Sanofi Vaccines US Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Flublok Trivalent Northern Hemisphere (INFLUENZA A VIRUS A/Missouri/11/2025 (H1N1) RECOMBINANT HEMAGGLUTININ ANTIGEN, INFLUENZA A VIRUS A/Darwin/1415/2025 (H3N2) RECOMBINANT HEMAGGLUTININ ANTIGEN, and INFLUENZA B VIRUS B/Pennsylvania/14/2025 RECOMBINANT HEMAGGLUTININ ANTIGEN).
What is the active ingredient?: Influenza a virus a/missouri/11/2025 (H1n1) recombinant hemagglutinin antigen, Influenza a virus a/darwin/1415/2025 (H3n2) recombinant hemagglutinin antigen, Influenza b virus b/pennsylvania/14/2025 recombinant hemagglutinin antigen.
Who is the labeler?: Sanofi Vaccines US Inc., NDC labeler code 49281. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Flublok Trivalent Northern Hemisphere?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.