What is NDC 50268-476?

50268-476 is the product NDC for Letrozole, Letrozole 2.5 mg/1 tablet, listed with the FDA by AvPAK. It has 1 package NDC, shown above in 10- and 11-digit form.

AvPAK, NDC labeler code 50268. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Letrozole?

22 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Letrozole NDC 50268-476 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)50268-476Labeler and product segments. Claims need a package NDC.

Product NDC at billing width50268-0476Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
50268-476-15	5026804761550268047615	50 BLISTER PACK in 1 BOX (50268-476-15) / 1 TABLET in 1 BLISTER PACK (50268-476-11)Marketed from Oct 2, 2019

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Letrozole
Generic name (nonproprietary): letrozole
Active ingredients: Letrozole — 2.5 mg/1
Dosage form: Tablet
Route: Oral
Labeler: AvPAKNDC labeler code 50268
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 200161
Marketing start: Oct 2, 2019
Listing expires: Dec 31, 2027
Other FDA classes: Aromatase Inhibitors (Mechanism)
Identifiers: Product ID 50268-476_48d4cf4a-83a7-4e5f-e063-6394a90a4eceSPL ID 48d4cf4a-83a7-4e5f-e063-6394a90a4eceSPL set ID 93f317f1-96d1-498e-e053-2995a90ac60dRxCUI 200064UNII 7LKK855W8I
Pharmacologic class: Aromatase Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N450268047615 followed by a unit qualifier and the quantity

Package 50268-0476-15. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jan 20, 2026.

Indications (excerpt from the label)

Letrozole tablets are an aromatase inhibitor indicated for: Adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer ( 1.1 ) Extended adjuvant treatment of postmenopausal women with early breast cancer who have received prior standard adjuvant tamoxifen therapy ( 1.2 ) First and second-line treatment of postmenopausal women with hormone receptor positive or unknown advanced breast cancer ( 1.3 ) 1.1 Adjuvant Treatment of Early Breast Cancer Letrozole tablets are indicated for the adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer. 1.2 Extended Adjuvant Treatment of Early Breast Cancer Letrozole tablets are indica…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 50268-476

What is NDC 50268-476?: 50268-476 is the product NDC for Letrozole, Letrozole 2.5 mg/1 tablet, listed with the FDA by AvPAK. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Letrozole.
What is the active ingredient?: Letrozole.
Who is the labeler?: AvPAK, NDC labeler code 50268. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Letrozole?: 22 other product NDCs are listed under this name. See all Letrozole NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Letrozole NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Letrozole	Letrozole 2.5 mg/1	Tablet, Film coatedOral	Carnegie Pharmaceuticals LLC	80005-139	80005-0139-0880005-0139-10
Letrozoleletrozole tablets	Letrozole 2.5 mg/1	Tablet, Film coatedOral	Upsher-Smith Laboratories, LLC	24979-726	24979-0726-07
Letrozoleletrozole tablets	Letrozole 2.5 mg/1	Tablet, Film coatedOral	Avet Pharmaceuticals Inc.	23155-875	23155-0875-0323155-0875-0923155-0875-10
Letrozoleletrozole tablets	Letrozole 2.5 mg/1	Tablet, Film coatedOral	Bryant Ranch Prepack	71335-2396	71335-2396-0171335-2396-0271335-2396-03+1 more
Letrozole	Letrozole 2.5 mg/1	Tablet, Film coatedOral	ATLANTIC BIOLOGICALS CORP.	17856-0032	17856-0032-01
Letrozoleletrozole tablets	Letrozole 2.5 mg/1	Tablet, Film coatedOral	Yiling Pharmaceutical, Inc.	69117-0004	69117-0004-01
Letrozole	Letrozole 2.5 mg/1	Tablet, Film coatedOral	Chartwell RX, LLC	62135-491	62135-0491-3062135-0491-90
Letrozole	Letrozole 2.5 mg/1	Tablet, Film coatedOral	Aurobindo Pharma Limited	59651-180	59651-0180-3059651-0180-90
Letrozoleletrozole tablets	Letrozole 2.5 mg/1	Tablet, Film coatedOral	Golden State Medical Supply, Inc.	51407-986	51407-0986-90
Letrozole	Letrozole 2.5 mg/1	Tablet, Film coatedOral	AvKARE	42291-374	42291-0374-3042291-0374-90

All 23 Letrozole NDCs

Other NDCs under ANDA 200161

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 200161
Product	Strength	Form · route	Labeler	Product NDC
Letrozole	Letrozole 2.5 mg/1	TabletOral	A-S Medication Solutions	50090-8002
Letrozole	Letrozole 2.5 mg/1	TabletOral	Breckenridge Pharmaceutical, Inc.	51991-759
Letrozole	Letrozole 2.5 mg/1	TabletOral	Natco Pharma Limited	63850-0025
Letrozole	Letrozole 2.5 mg/1	TabletOral	Bryant Ranch Prepack	71335-1526