What is NDC 51662-1588?

51662-1588 is the product NDC for BUPIVACAINE HCl, Bupivacaine hydrochloride 5 mg/mL injection, solution, listed with the FDA by HF Acquisition Co LLC, DBA HealthFirst. It has 1 package NDC, shown above in 10- and 11-digit form.

HF Acquisition Co LLC, DBA HealthFirst, NDC labeler code 51662. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for BUPIVACAINE HCl?

8 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

BUPIVACAINE HCl NDC 51662-1588 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)51662-1588Labeler and product segments. Claims need a package NDC.

Product NDC at billing width51662-1588Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
51662-1588-3	5166215880351662158803	25 POUCH in 1 CASE (51662-1588-3) / 1 VIAL, MULTI-DOSE in 1 POUCH (51662-1588-2) / 50 mL in 1 VIAL, MULTI-DOSEMarketed from Jul 11, 2022

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): BUPIVACAINE HCl
Generic name (nonproprietary): bupivacaine hcl
Active ingredients: Bupivacaine hydrochloride — 5 mg/mL
Dosage form: Injection, Solution
Route: Perineural
Labeler: HF Acquisition Co LLC, DBA HealthFirstNDC labeler code 51662
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 018304
Marketing start: Jul 11, 2022
Listing expires: Dec 31, 2027
Other FDA classes: Amides (Chemical structure)Local Anesthesia (Physiologic effect)
Identifiers: Product ID 51662-1588_54ddbb1d-c786-9987-e063-6294a90adabdSPL ID 54ddbb1d-c786-9987-e063-6294a90adabdSPL set ID e391f807-7699-6d82-e053-2a95a90ab641RxCUI 1012396, 1012404UNII 7TQO7W3VT8
Pharmacologic class: Amide Local Anesthetic

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

NDC on a medical claim

N451662158803 followed by a unit qualifier and the quantity

Package 51662-1588-03. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jun 22, 2026. This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS & USAGE Sensorcaine (bupivacaine HCl) is indicated for the production of local or regional anesthesia or analgesia for surgery, dental and oral surgery procedures, diagnostic and therapeutic procedures, and for obstetrical procedures. Only the 0.25% and 0.5% concentrations are indicated for obstetrical anesthesia (see WARNINGS ). Experience with nonobstetrical surgical procedures in pregnant patients is not sufficient to recommend use of the 0.75% concentration of bupivacaine HCl in these patients. Sensorcaine is not recommended for intravenous regional anesthesia (Bier Block) (see WARNINGS ). The routes of administration and indicated Sensorcaine concentrations are: See DOSAGE A…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 51662-1588

What is NDC 51662-1588?: 51662-1588 is the product NDC for BUPIVACAINE HCl, Bupivacaine hydrochloride 5 mg/mL injection, solution, listed with the FDA by HF Acquisition Co LLC, DBA HealthFirst. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: BUPIVACAINE HCl.
What is the active ingredient?: Bupivacaine hydrochloride.
Who is the labeler?: HF Acquisition Co LLC, DBA HealthFirst, NDC labeler code 51662. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for BUPIVACAINE HCl?: 8 other product NDCs are listed under this name. See all BUPIVACAINE HCl NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other BUPIVACAINE HCl NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Bupivacaine HClbupivacaine hydrochloride	Bupivacaine hydrochloride 2.5 mg/mL	Injection, SolutionPerineural	Xellia Pharmaceuticals USA LLC	70594-116	70594-0116-01
Bupivacaine HClbupivacaine hydrochloride	Bupivacaine hydrochloride 5 mg/mL	Injection, SolutionPerineural	Xellia Pharmaceuticals USA LLC	70594-119	70594-0119-01
Bupivacaine HClbupivacaine hydrochloride	Bupivacaine hydrochloride 2.5 mg/mL	Injection, SolutionEpidural, Intracaudal, Perineural	Xellia Pharmaceuticals USA LLC	70594-114	70594-0114-02
BUPIVACAINE HClbupivacaine hydrochloride	Bupivacaine hydrochloride 2.5 mg/mL	Injection, SolutionEpidural, Intracaudal, Perineural	Xellia Pharmaceuticals USA LLC	70594-115	70594-0115-01
Bupivacaine HClbupivacaine hydrochloride	Bupivacaine hydrochloride 5 mg/mL	Injection, SolutionEpidural, Intracaudal, Perineural	Xellia Pharmaceuticals USA LLC	70594-117	70594-0117-02
Bupivacaine HClbupivacaine hydrochloride	Bupivacaine hydrochloride 5 mg/mL	Injection, SolutionEpidural, Intracaudal, Perineural	Xellia Pharmaceuticals USA LLC	70594-118	70594-0118-01
Bupivacaine HClbupivacaine hydrochloride	Bupivacaine hydrochloride 7.5 mg/mL	Injection, SolutionEpidural, Intracaudal, Perineural	Xellia Pharmaceuticals USA LLC	70594-120	70594-0120-02
BUPIVACAINE HCl	Bupivacaine hydrochloride 2.5 mg/mL	Injection, SolutionInfiltration, Perineural	HF Acquisition Co LLC, DBA HealthFirst	51662-1592	51662-1592-03

Other NDCs under NDA 018304

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 018304
Product	Strength	Form · route	Labeler	Product NDC
BUPIVACAINE HCl	Bupivacaine hydrochloride 2.5 mg/mL	Injection, SolutionInfiltration, Perineural	HF Acquisition Co LLC, DBA HealthFirst	51662-1592
Sensorcainebupivacaine hydrochloride	Bupivacaine hydrochloride 2.5 mg/mL	Injection, SolutionInfiltration, Perineural	Henry Schein, Inc.	0404-9945
Sensorcainebupivacaine hydrochloride	Bupivacaine hydrochloride 5 mg/mL	Injection, SolutionPerineural	Henry Schein, Inc.	0404-9947
Sensorcainebupivacaine hydrochloride	Bupivacaine hydrochloride 2.5 mg/mL	Injection, SolutionInfiltration, Perineural	Fresenius Kabi USA, LLC	63323-465
Sensorcainebupivacaine hydrochloride	Bupivacaine hydrochloride 5 mg/mL	Injection, SolutionPerineural	Fresenius Kabi USA, LLC	63323-467
Sensorcaine Mpfbupivacaine hydrochloride and epinephrine bitartrate	Bupivacaine hydrochloride 7.5 mg/mL; Epinephrine bitartrate .005 mg/mL	Injection, SolutionEpidural, Retrobulbar	Fresenius Kabi USA, LLC	63323-460
Sensorcaine Mpfbupivacaine hydrochloride and epinephrine bitartrate	Bupivacaine hydrochloride 5 mg/mL; Epinephrine bitartrate .005 mg/mL	Injection, SolutionEpidural, Intracaudal, Perineural	Fresenius Kabi USA, LLC	63323-462
Sensorcaine Mpfbupivacaine hydrochloride	Bupivacaine hydrochloride 5 mg/mL	Injection, SolutionEpidural, Infiltration, Intracaudal, Perineural	Fresenius Kabi USA, LLC	63323-466