What is NDC 58228-2045?

58228-2045 is the product NDC for Hydrocortisone 1%, Hydrocortisone 1 g/100g cream, listed with the FDA by ProStat First Aid LLC. It has 1 package NDC, shown above in 10- and 11-digit form.

ProStat First Aid LLC, NDC labeler code 58228. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Hydrocortisone 1%?

14 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Hydrocortisone 1% NDC 58228-2045 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)58228-2045Labeler and product segments. Claims need a package NDC.

Product NDC at billing width58228-2045Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
58228-2045-2	5822820450258228204502	1800 BOX in 1 CASE (58228-2045-2) / 25 PACKET in 1 BOX (58228-2045-1) / .9 g in 1 PACKETMarketed from Apr 10, 2023

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Hydrocortisone 1%
Generic name (nonproprietary): hydrocortisone 1%
Active ingredients: Hydrocortisone — 1 g/100g
Dosage form: Cream
Route: Topical
Labeler: ProStat First Aid LLCNDC labeler code 58228
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 032
Marketing start: Apr 10, 2023
Listing expires: Dec 31, 2026
Other FDA classes: Corticosteroid Hormone Receptor Agonists (Mechanism)
Identifiers: Product ID 58228-2045_46013b99-8359-912c-e063-6294a90a1050SPL ID 46013b99-8359-912c-e063-6294a90a1050SPL set ID f707bda4-074a-6406-e053-6394a90a7ae1RxCUI 106258UNII WI4X0X7BPJUPC 0814889010179
Pharmacologic class: Corticosteroid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N458228204502 followed by a unit qualifier and the quantity

Package 58228-2045-02. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Dec 15, 2025.

Indications (excerpt from the label)

Use(s) For the temporary relief of itching associated with minor skin irritations, inflammation, and rashes due to eczema, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics, jewelry, seborrheic dermatitis, psoriasis, and for external genital, feminine, and anal itching

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 58228-2045

What is NDC 58228-2045?: 58228-2045 is the product NDC for Hydrocortisone 1%, Hydrocortisone 1 g/100g cream, listed with the FDA by ProStat First Aid LLC. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Hydrocortisone 1%.
What is the active ingredient?: Hydrocortisone.
Who is the labeler?: ProStat First Aid LLC, NDC labeler code 58228. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Hydrocortisone 1%?: 14 other product NDCs are listed under this name. See all Hydrocortisone 1% NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Hydrocortisone 1% NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Hydrocortisone 1%hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Preferred Pharmaceuticals Inc.	68788-4109	68788-4109-02
Hydrocortisone 1%hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	ProStat First Aid	58228-7020	58228-7020-01
Hydrocortisone 1%hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	ProStat First Aid	58228-7030	58228-7030-01
Hydrocortisone 1%hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	ProStat First Aid	58228-7090	58228-7090-01
Hydrocortisone 1%hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Chain Drug Marketing Association Inc.	83324-329	83324-0329-01
Hydrocortisone 1%hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Chain Drug Marketing Association Inc.	83324-047	83324-0047-01
Hydrocortisone 1%hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Trifecta Pharmaceuticals Usa Llc	69396-129	69396-0129-01
Hydrocortisone 1%hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Geri-Care Pharmaceuticals, Corp	57896-146	57896-0146-14
Hydrocortisone 1%hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Trifecta Pharmaceuticals Usa Llc	69396-118	69396-0118-0969396-0118-25
Hydrocortisone 1%hydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Trifecta Pharmaceuticals Usa Llc	69396-081	69396-0081-01

All 15 Hydrocortisone 1% NDCs

Other NDCs under M 032

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 032
Product	Strength	Form · route	Labeler	Product NDC
111MedCo Medicated Bar 2 Pyrithione Zincpyrithione zinc	Pyrithione zinc 20 mg/g	SoapTopical	111MedCo LLC	72811-002
13.5oz 2 In 1 Dandruff Hair Cleanse and Conditioner - Eucalyptus and Mintpyrithione zinc	Pyrithione zinc .5 g/100mL	ShampooTopical	Rejoice International Corp.	57337-178
13.5oz 2 In 1 Dandruff Hair Cleanse and Conditioner - Eucalyptus and Mintpyrithione zinc shampoo	Pyrithione zinc .5 g/100mL	ShampooTopical	China Ningbo Shangge Cosmetics Technology Corp.	58503-210
13.5oz 2 In 1 Dandruff Hair Cleanse and Conditioner - Shea and Cocoa Butterpyrithione zinc	Pyrithione zinc .5 g/100mL	ShampooTopical	Rejoice International Corp.	57337-179
13.5oz 2 In 1 Dandruff Hair Cleanse and Conditioner - Shea and Cocoa Butterpyrithione zinc shampoo	Pyrithione zinc .5 g/100mL	ShampooTopical	China Ningbo Shangge Cosmetics Technology Corp.	58503-211
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	Target Corporation	11673-643
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	Better Living Brands, LLC	21130-942
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	H E B	37808-311
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	H E B	37808-612
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	United Natural Foods, Inc. dba UNFI	41163-266
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	Old East Main Co.	55910-311
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	Old East Main Co.	55910-496
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	Old East Main Co.	55910-921
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	Old East Main Co.	55910-942
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	Aldi, Inc	64024-311
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	Retail Business Services, LLC	72476-362
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	Retail Business Services, LLC	72476-612
2 in 1 Dandruffpyrithione zinc	Pyrithione zinc 10 mg/mL	ShampooTopical	Topco Associates LLC	76162-362
5% Minoxidil and 5% Rosemary for Hair Careminoxidil	Minoxidil 5 g/100mL; Rosemary 5 g/100mL	LiquidTopical	TIKNOW LLC	84454-001
5% MINOXIDIL HAIR REGROWTH SERUM With Biotinminoxidil	Minoxidil 5 g/100mL; Biotin .2 g/100mL	SolutionTopical	Shenzhen Ctrip Technology Co., Ltd.	84614-001

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