NDC codes

FDA NDC Directory
Product NDC (as listed)58468-0348Labeler and product segments. Claims need a package NDC.
Product NDC at billing width58468-0348Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
58468-0348-1584680348011 SYRINGE in 1 CARTON (58468-0348-1) / .5 mL in 1 SYRINGEMarketed from Mar 28, 2025

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Qfitlia
Generic name (nonproprietary)
fitusiran
Active ingredients
Fitusiran — 50 mg/.5mL
Dosage form
Injection, Solution
Route
Subcutaneous
Labeler
Genzyme CorporationNDC labeler code 58468
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 219019
Marketing start
Listing expires
Other FDA classes
Decreased RNA Integrity (Physiologic effect)Increased RNA Degradation (Physiologic effect)Small Interfering (Chemical structure)
Identifiers
Product ID 58468-0348_1c225007-61f2-4c48-a25e-f08b8d356a59SPL ID 1c225007-61f2-4c48-a25e-f08b8d356a59SPL set ID 6dd2f8ac-6f90-4cbf-b197-97d74964135cRxCUI 2709452, 2709458, 2709461, 2709464UNII SV9W47ZLE1
Pharmacologic class
Antithrombin-directed RNA Interaction; Small Interfering RNA

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N458468034801 followed by a unit qualifier and the quantity

Package 58468-0348-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

QFITLIA is indicated for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in adult and pediatric patients aged 12 years and older with hemophilia A or B with or without factor VIII or IX inhibitors. QFITLIA is an antithrombin-directed small interfering ribonucleic acid indicated for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in adult and pediatric patients aged 12 years and older with hemophilia A or B with or without factor VIII or IX inhibitors. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 58468-0348

What is NDC 58468-0348?
58468-0348 is the product NDC for Qfitlia (fitusiran), Fitusiran 50 mg/.5mL injection, solution, listed with the FDA by Genzyme Corporation. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?
Qfitlia (Fitusiran).
What is the active ingredient?
Fitusiran.
Who is the labeler?
Genzyme Corporation, NDC labeler code 58468. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Qfitlia?
1 other product NDC are listed under this name. See all Qfitlia NDCs.
Is there a related HCPCS / J-code?
Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Qfitlia NDCs
ProductStrengthForm · routeLabelerProduct NDCPackage NDCs (11-digit)
QfitliafitusiranFitusiran 20 mg/.2mLInjection, SolutionSubcutaneousGenzyme Corporation58468-034758468-0347-01

Other NDCs under NDA 219019

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 219019
ProductStrengthForm · routeLabelerProduct NDC
QfitliafitusiranFitusiran 20 mg/.2mLInjection, SolutionSubcutaneousGenzyme Corporation58468-0347

Free account

Keep searching with a free account

You’ve used your 3 free searches for this session. Log in or create a free Med-Code account to keep looking up NDCs, J-codes and drugs.

Create a free accountLog in