What is NDC 59428-403?

59428-403 is the product NDC for Quadrydern (hydrocortisone), Hydrocortisone 10 mg/g cream, listed with the FDA by Productos Zapotol Corp. It has 1 package NDC, shown above in 10- and 11-digit form.

Productos Zapotol Corp, NDC labeler code 59428. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Quadrydern?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Quadrydern NDC 59428-403 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)59428-403Labeler and product segments. Claims need a package NDC.

Product NDC at billing width59428-0403Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
59428-403-57	5942804035759428040357	1 TUBE in 1 CARTON (59428-403-57) / 57 g in 1 TUBEMarketed from Mar 11, 2020

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Quadrydern
Generic name (nonproprietary): hydrocortisone
Active ingredients: Hydrocortisone — 10 mg/g
Dosage form: Cream
Route: Topical
Labeler: Productos Zapotol CorpNDC labeler code 59428
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 016
Marketing start: Mar 11, 2020
Listing expires: Dec 31, 2026
Other FDA classes: Corticosteroid Hormone Receptor Agonists (Mechanism)
Identifiers: Product ID 59428-403_41b49031-48b5-b9bf-e063-6394a90a7f07SPL ID 41b49031-48b5-b9bf-e063-6394a90a7f07SPL set ID a087ad4d-9a65-19c3-e053-2995a90ab341RxCUI 106258UNII WI4X0X7BPJUPC 0647755001403
Pharmacologic class: Corticosteroid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N459428040357 followed by a unit qualifier and the quantity

Package 59428-0403-57. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Oct 21, 2025.

Indications (excerpt from the label)

Directions for itching of skin irritation, inflammation, and rashes: adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily. children under 2 years of age: ask a doctor Adults: for external anal itching: for external anal and genital itching, adults: when practical, clean the affected area with mild soap and warm water and rinse thoroughly gently dry by patting or blotting with toilet tissue or a soft cloth before applying apply to affected area not more than 3 to 4 times daily children under 12 years of age: ask a doctor

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 59428-403

What is NDC 59428-403?: 59428-403 is the product NDC for Quadrydern (hydrocortisone), Hydrocortisone 10 mg/g cream, listed with the FDA by Productos Zapotol Corp. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Quadrydern (Hydrocortisone).
What is the active ingredient?: Hydrocortisone.
Who is the labeler?: Productos Zapotol Corp, NDC labeler code 59428. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Quadrydern?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other NDCs under M 016

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 016
Product	Strength	Form · route	Labeler	Product NDC
2-Pack Facial Serum	Water 78.894 g/100mL + 4 more ingredients	LiquidCutaneous	Guangzhou Ariel Biotech Co., Ltd.	84148-011
2-Pack Facial Serum	3-o-ethyl ascorbic acid .5 g/100mL + 3 more ingredients	LiquidCutaneous	Guangzhou Ariel Biotech Co., Ltd.	84148-012
3M Cavilon Durable Barrierdimethicone	Dimethicone 13000 mg/L	CreamTopical	Solventum US LLC	17518-030
4% 10gTATTOO Numb Cream4% lidocaine	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-031
4% TATTOO Numb Cream4% lidocaine	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-030
456 Acne Relief Creamniacinamide,salicylic acid,centella asiatica root,coptis chinensis root	Salicylic acid 380 mg/50g + 3 more ingredients	CreamTopical	Guangzhou Senmai Biotechnology Co.,Ltd.	84509-111
5% Dr.care Numb creamlidocaine	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-028
5% Minoxidil	Minoxidil 2 g/100g + 3 more ingredients	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-328
5% Minoxidil	Minoxidil 2 g/100g + 3 more ingredients	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-329
5% Minoxidil	Biotin .05 g/100g; Niacinamide 2.5 g/100g	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-335
5% Minoxidil	Minoxidil 5 g/100g + 5 more ingredients	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-337
5% Minoxidil for Men and Women	Biotin .05 g/100g; Tocopherol .05 g/100g	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-332
5% Minoxidil Hair Growth	Biotin .1 g/100g + 3 more ingredients	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-333
5% Minoxidil Hair Growth	Minoxidil 5 g/100g + 3 more ingredients	SprayCutaneous	Guangzhou Yanxi Biotechnology Co., Ltd	84025-334
5% Signature Numb creamlidocaine	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-026
5% Signature Numb cream5% signature	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-027
5% Signature Numb cream5% lidocaine	Lidocaine 100 mg/g	CreamCutaneous	Shengnan (Guangzhou) Cosmetics Co., LTD	84019-029
70% Isopropyl Rubbing Alcoholisopropyl alcohol	Isopropyl alcohol 70 mL/100mL	LiquidTopical	MY IMPORTS USA LLC	51628-4501
911allantoin	Allantoin .5 g/100g	OintmentTopical	Skinfix, Inc.	61328-120
A and Dpetrolatum	Petrolatum 76 g/100g	OintmentTopical	Safetec of America, Inc.	61010-4405

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Quadrydern (Hydrocortisone) NDC 59428-403