What is NDC 59746-221?

59746-221 is the product NDC for Risperidone, Risperidone .25 mg/1 tablet, listed with the FDA by Jubilant Cadista Pharmacuticals Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.

Jubilant Cadista Pharmacuticals Inc., NDC labeler code 59746. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Risperidone?

168 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Risperidone NDC 59746-221 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)59746-221Labeler and product segments. Claims need a package NDC.

Product NDC at billing width59746-0221Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
59746-221-05	5974602210559746022105	500 TABLET in 1 BOTTLE (59746-221-05)Marketed from Oct 15, 2025
59746-221-60	5974602216059746022160	60 TABLET in 1 BOTTLE (59746-221-60)Marketed from Oct 15, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Risperidone
Generic name (nonproprietary): risperidone
Active ingredients: Risperidone — .25 mg/1
Dosage form: Tablet
Route: Oral
Labeler: Jubilant Cadista Pharmacuticals Inc.NDC labeler code 59746
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 078828
Marketing start: Oct 15, 2025
Listing expires: Dec 31, 2027
Identifiers: Product ID 59746-221_39d41b28-93eb-446b-9652-7432858ccbabSPL ID 39d41b28-93eb-446b-9652-7432858ccbabSPL set ID 39d41b28-93eb-446b-9652-7432858ccbabRxCUI 312828, 312829, 312830, 312831, 312832, 314211UNII L6UH7ZF8HC
Pharmacologic class: Atypical Antipsychotic

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N459746022105 followed by a unit qualifier and the quantity

Package 59746-0221-05. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jul 2, 2025. This label includes a boxed warning.

Indications (excerpt from the label)

Risperidone is atypical antipsychotic indicated for: Treatment of schizophrenia ( 1.1 ) As monotherapy or adjunctive therapy with lithium or valproate, for the treatment of acute manic or mixed episodes associated with Bipolar I Disorder ( 1.2) Treatment of irritability associated with autistic disorder ( 1.3 ) 1.1 Schizophrenia Risperidone tablets are indicated for the treatment of schizophrenia. Efficacy was established in 4 short-term trials in adults, 2 short-term trials in adolescents (ages 13 to 17 years), and one long-term maintenance trial in adults [see Clinical Studies (14.1) ] . 1.2 Bipolar Mania Monotherapy Risperidone tablets are indicated for the treatment of acute manic or mix…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 59746-221

What is NDC 59746-221?: 59746-221 is the product NDC for Risperidone, Risperidone .25 mg/1 tablet, listed with the FDA by Jubilant Cadista Pharmacuticals Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Risperidone.
What is the active ingredient?: Risperidone.
Who is the labeler?: Jubilant Cadista Pharmacuticals Inc., NDC labeler code 59746. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Risperidone?: 168 other product NDCs are listed under this name. See all Risperidone NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Risperidone NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Risperidone	Risperidone .5 mg/1	Tablet, Orally disintegratingOral	Amerisyn LLC	87564-013	87564-0013-28
Risperidone	Risperidone 1 mg/1	Tablet, Orally disintegratingOral	Amerisyn LLC	87564-014	87564-0014-28
Risperidone	Risperidone 2 mg/1	Tablet, Orally disintegratingOral	Amerisyn LLC	87564-015	87564-0015-28
Risperidone	Risperidone 3 mg/1	Tablet, Orally disintegratingOral	Amerisyn LLC	87564-016	87564-0016-28
Risperidone	Risperidone 4 mg/1	Tablet, Orally disintegratingOral	Amerisyn LLC	87564-017	87564-0017-28
Risperidone	Risperidone .5 mg/1	TabletOral	Coupler LLC	67046-0644	67046-0644-03
Risperidone	Risperidone .25 mg/1	TabletOral	Coupler LLC	67046-2064	67046-2064-03
Risperidone	Risperidone 1 mg/1	TabletOral	Coupler LLC	67046-0635	67046-0635-03
Risperidone	Risperidone 2 mg/1	TabletOral	Coupler LLC	67046-0630	67046-0630-03
Risperidone	Risperidone .5 mg/1	Tablet, Orally disintegratingOral	Amici Pharma, Inc.	69292-571	69292-0571-30

All 169 Risperidone NDCs

Other NDCs under ANDA 078828

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 078828
Product	Strength	Form · route	Labeler	Product NDC
Risperidone	Risperidone .5 mg/1	TabletOral	Jubilant Cadista Pharmacuticals Inc.	59746-222
Risperidone	Risperidone 1 mg/1	TabletOral	Jubilant Cadista Pharmacuticals Inc.	59746-223
Risperidone	Risperidone 2 mg/1	TabletOral	Jubilant Cadista Pharmacuticals Inc.	59746-224
Risperidone	Risperidone 3 mg/1	TabletOral	Jubilant Cadista Pharmacuticals Inc.	59746-225
Risperidone	Risperidone 4 mg/1	TabletOral	Jubilant Cadista Pharmacuticals Inc.	59746-226
Risperidone	Risperidone .25 mg/1	TabletOral	Golden State Medical Supply, Inc.	84677-002
Risperidone	Risperidone .5 mg/1	TabletOral	Golden State Medical Supply, Inc.	84677-003
Risperidone	Risperidone 1 mg/1	TabletOral	Golden State Medical Supply, Inc.	84677-004
Risperidone	Risperidone 2 mg/1	TabletOral	Golden State Medical Supply, Inc.	84677-005
Risperidone	Risperidone 3 mg/1	TabletOral	Golden State Medical Supply, Inc.	84677-006
Risperidone	Risperidone 4 mg/1	TabletOral	Golden State Medical Supply, Inc.	84677-007