NDC codes

FDA NDC Directory
Product NDC (as listed)64380-225Labeler and product segments. Claims need a package NDC.
Product NDC at billing width64380-0225Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
64380-225-016438002250160 TABLET in 1 BOTTLE (64380-225-01)Marketed from May 14, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Doxycycline Hyclate
Generic name (nonproprietary)
doxycycline hyclate
Active ingredients
Doxycycline hyclate — 50 mg/1
Dosage form
Tablet
Route
Oral
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 062538
Marketing start
Listing expires
Other FDA classes
Tetracyclines (Chemical structure)
Identifiers
Product ID 64380-225_6c0d6056-c09d-4cd8-85a2-e9e2a96aa6fdSPL ID 6c0d6056-c09d-4cd8-85a2-e9e2a96aa6fdSPL set ID 2deeee4f-b342-a178-e063-6394a90af897RxCUI 1652674UNII 19XTS3T51UUPC 0364380225010
Pharmacologic class
Tetracycline-class Drug

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N464380022501 followed by a unit qualifier and the quantity

Package 64380-0225-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

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