What is NDC 65219-222?

65219-222 is the product NDC for Sodium chloride, Sodium chloride 9 mg/mL injection, solution, listed with the FDA by Fresenius Kabi USA, LLC. It has 1 package NDC, shown above in 10- and 11-digit form.

Fresenius Kabi USA, LLC, NDC labeler code 65219. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Sodium chloride?

116 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Sodium chloride NDC 65219-222 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)65219-222Labeler and product segments. Claims need a package NDC.

Product NDC at billing width65219-0222Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
65219-222-25	6521902222565219022225	30 BAG in 1 CASE (65219-222-25) / 250 mL in 1 BAG (65219-222-01)Marketed from Nov 17, 2021

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Sodium chloride
Generic name (nonproprietary): sodium chloride
Active ingredients: Sodium chloride — 9 mg/mL
Dosage form: Injection, Solution
Route: Intravenous
Labeler: Fresenius Kabi USA, LLCNDC labeler code 65219
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 207310
Marketing start: Sep 19, 2017
Listing expires: Dec 31, 2027
Other FDA classes: Increased Large Intestinal Motility (Physiologic effect)Inhibition Large Intestine Fluid/Electrolyte Absorption (Physiologic effect)Osmotic Activity (Mechanism)
Identifiers: Product ID 65219-222_d5c0c612-d7b8-458f-8ad3-d3999b3bd89dSPL ID d5c0c612-d7b8-458f-8ad3-d3999b3bd89dSPL set ID d98bf9f7-30ec-4927-a577-cabad192cb18RxCUI 1807631, 1807632, 1807633, 1807634UNII 451W47IQ8X
Pharmacologic class: Osmotic Laxative

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N465219022225 followed by a unit qualifier and the quantity

Package 65219-0222-25. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jan 19, 2026.

Indications (excerpt from the label)

INDICATIONS AND USAGE Intravenous solutions containing sodium chloride are indicated for parenteral replenishment of fluid and sodium chloride as required by the clinical condition of the patient.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 65219-222

What is NDC 65219-222?: 65219-222 is the product NDC for Sodium chloride, Sodium chloride 9 mg/mL injection, solution, listed with the FDA by Fresenius Kabi USA, LLC. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Sodium chloride.
What is the active ingredient?: Sodium chloride.
Who is the labeler?: Fresenius Kabi USA, LLC, NDC labeler code 65219. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Sodium chloride?: 116 other product NDCs are listed under this name. See all Sodium chloride NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Sodium chloride NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Sodium Chloride	Sodium chloride 50 mg/g	OintmentOphthalmic	YYBA CORP	73581-707	73581-0707-0173581-0707-03
Sodium Chloride	Sodium chloride 1 g/1	TabletOral	Method Pharmaceuticals, LLC	58657-119	58657-0119-01
Sodium chloride	Sodium chloride .9 g/100mL	Injection, SolutionIrrigation	Fresenius Kabi USA, LLC	65219-502	65219-0502-10
Sodium chloride	Sodium chloride .9 g/100mL	Injection, SolutionIrrigation	Fresenius Kabi USA, LLC	65219-504	65219-0504-20
Sodium chloride	Sodium chloride .9 g/100mL	Injection, SolutionIrrigation	Becton Dickinson and Company	17271-800	17271-0800-0717271-0800-0817271-0800-09
Sodium Chloride	Sodium chloride 1000 mg/1	TabletOral	Rising Pharma Holdings, Inc.	57237-361	57237-0361-01
Sodium chloride	Sodium chloride .9 g/100mL	Injection, SolutionIrrigation	Fresenius Kabi USA, LLC	65219-506	65219-0506-30
Sodium Chloridesodium chloride tablets	Sodium chloride 1000 mg/1	TabletOral	Kesin Pharma Corporation	81033-028	81033-0028-01
Sodium Chloridesodium chloride tablet	Sodium chloride 1000 mg/1	TabletOral	Belleview Bioscience LLC	84447-002	84447-0002-01
Sodium Chloride	Sodium chloride 900 mg/100mL	IrrigantIrrigation	Baxter Healthcare Company	0338-9834	00338-9834-04

All 117 Sodium chloride NDCs

Other NDCs under ANDA 207310

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 207310
Product	Strength	Form · route	Labeler	Product NDC
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	63323-623
Sodium Chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	63323-632
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	65219-218
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	65219-220
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	65219-224
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	65219-282
Sodium Chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	65219-328
Sodium Chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	65219-432
0.9% Sodium Chloridesodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	HF Acquisition Co LLC, DBA HealthFirst	51662-1577
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	65219-466
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	65219-474
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	65219-468
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	65219-470
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Fresenius Kabi USA, LLC	65219-472
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	Becton Dickinson and Company	17271-701
Sodium chloride	Sodium chloride 9 mg/mL	Injection, SolutionIntravenous	BECTON DICKINSON AND COMPANY	17271-771